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产品描述:小鼠基质金属蛋白酶抑制因子1(TIMP-1)酶联免疫试剂盒为双抗夹心法ELISA试剂盒,定量检测血清、血浆、组织培养上清液样本中的TIMP1含量。TIMP1 即金属蛋白酶组织抑制因子 1,在多种组织和细胞中表达。它能抑制基质金属蛋白酶活性,调节细胞外基质的代谢。在肿瘤领域,TIMP1 与肿瘤的发生、发展、侵袭和转移密切相关,还可作为肿瘤诊断和预后评估的潜在标志物。试剂盒检测范围为0.156 ng/mL-10 ng/mL,灵敏度为0.110 ng/mL。探究组织纤维化机制、肿瘤微环境调控、炎症性疾病模型中的基质动态变化,或评估药物干预对MMP/TIMP平衡的影响本品仅用于科研,不用于临床诊断,产品具体参数及操作步骤详见产品说明书。
别名:Timp1 ELISA Kit; Timp ELISA Kit; Timp-1 ELISA Kit; Metalloproteinase inhibitor 1 ELISA Kit; Collagenase inhibitor 16C8 fibroblast ELISA Kit; Erythroid-potentiating activity ELISA Kit; EPA ELISA Kit; TPA-S1 ELISA Kit; TPA-induced protein ELISA Kit; Tissue inhibitor of metalloproteinases 1 ELISA Kit; TIMP-1 ELISA Kit
缩写:TIMP1
Uniprot No.:P12032
种属:Mus musculus (Mouse)
样本类型:serum, plasma, cell culture supernates
检测范围:0.156 ng/mL-10 ng/mL
灵敏度:0.110 ng/mL
反应时间:1-5h
样本体积:50-100ul
检测波长:450 nm
研究领域:Cardiovascular
测定原理:quantitative
测定方法:Sandwich
精密度:
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays):CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
线性度:
To assess the linearity of the assay, samples were spiked with high concentrations of mouse TIMP-1in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
标准曲线:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
货期:3-5 working days
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