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产品描述:人基质金属蛋白酶组织抑制因子1(TIMP-1)酶联免疫试剂盒为双抗夹心法ELISA试剂盒,定量检测血清、血浆、组织匀浆样本中的TIMP1含量。TIMP1是一种金属蛋白酶抑制剂,通过与胶原酶等金属蛋白酶结合,抑制其活性,调节细胞分化、迁移和死亡等过程。研究显示,TIMP1缺陷可促进前列腺癌转移,其机制是通过激活基质金属蛋白酶(MMP)重编程衰老肿瘤细胞的衰老相关分泌表型(SASP)。此外,TIMP1蛋白还能增强免疫系统对抗癌症。试剂盒检测范围为0.39 ng/mL-25 ng/mL,灵敏度为0.434 ng/mL。适用于体外研究TIMP-1在组织修复、慢性炎症或肿瘤微环境中的作用机制,为心血管疾病、肝纤维化及癌症等领域的分子机制探索提供可靠工具。满足科研场景中对低丰度蛋白的精准定量需求。本品仅用于科研,不用于临床诊断,产品具体参数及操作步骤详见产品说明书。
别名:Clgi ELISA Kit; Collagenase inhibitor ELISA Kit; Collagenase inhibitor; Human ELISA Kit; EPA ELISA Kit; EPO ELISA Kit; Erythroid Potentiating Activity ELISA Kit; Erythroid-potentiating activity ELISA Kit; Fibroblast collagenase inhibitor ELISA Kit; FLJ90373 ELISA Kit; HCI ELISA Kit; Human Collagenase Inhibitor ELISA Kit; Metalloproteinase inhibitor 1 ELISA Kit; Metalloproteinase inhibitor 1 precursor ELISA Kit; OTTHUMP00000023214 ELISA Kit; TIMP 1 ELISA Kit; TIMP ELISA Kit; TIMP metallopeptidase inhibitor 1 ELISA Kit; TIMP-1 ELISA Kit; Timp1 ELISA Kit; TIMP1 protein ELISA Kit; TIMP1_HUMAN ELISA Kit; Tissue Inhibitor of Metalloproteinase 1 ELISA Kit; Tissue inhibitor of metalloproteinases 1 ELISA Kit; Tissue inhibitor of metalloproteinases ELISA Kit; Ttissue inhibitor of metalloproteinase 1 erythroid potentiating activity collagenase inhibitor ELISA Kit
缩写:TIMP1
Uniprot No.:P01033
种属:Homo sapiens (Human)
样本类型:serum, plasma, tissue homogenates
检测范围:0.39 ng/mL-25 ng/mL
灵敏度:0.434 ng/mL
反应时间:1-5h
样本体积:50-100ul
检测波长:450 nm
研究领域:Cardiovascular
测定原理:quantitative
测定方法:Sandwich
精密度:
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays):CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
线性度:
To assess the linearity of the assay, samples were spiked with high concentrations of human Timp-1 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
标准曲线:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
货期:3-5 working days
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