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产品描述:人可溶性Endoglin(sENG/sCD105)酶联免疫试剂盒为双抗夹心法ELISA试剂盒,定量检测血清、血浆、组织匀浆样本中的ENG含量。ENG(内皮糖蛋白)是一种主要表达于内皮细胞的跨膜糖蛋白。它参与TGF - β信号通路,在血管生成、细胞粘附和迁移等过程中发挥重要作用。目前围绕它在肿瘤血管生成、心血管疾病中的机制研究较多,有望作为治疗靶点开发相关药物。试剂盒检测范围为0.156 ng/mL-10 ng/mL,灵敏度为0.047 ng/mL。试剂盒适用于心血管生物学、肿瘤微环境研究等领域,可帮助科研人员定量分析疾病模型中Endoglin的表达动态,探索其与血管功能障碍的分子机制关联。该产品严格遵循科研用途开发,适用于基础医学研究、药物靶点验证及生物标志物探索等非诊断性研究场景。本品仅用于科研,不用于临床诊断,产品具体参数及操作步骤详见产品说明书。
别名:ENG; END; Endoglin; CD antigen CD105
缩写:ENG
Uniprot No.:P17813
种属:Homo sapiens (Human)
样本类型:serum, plasma, tissue homogenates
检测范围:0.156 ng/mL-10 ng/mL
灵敏度:0.047 ng/mL
反应时间:1-5h
样本体积:50-100ul
检测波长:450 nm
研究领域:Cancer
测定原理:quantitative
测定方法:Sandwich
精密度:
Intra-assay Precision (Precision within an assay): CV%<8%
Three samples of known concentration were tested twenty times on one plate to assess.
Inter-assay Precision (Precision between assays):CV%<10%
Three samples of known concentration were tested in twenty assays to assess.
线性度:
To assess the linearity of the assay, samples were spiked with high concentrations of human sCD105 in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
标准曲线:
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
货期:3-5 working days
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