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产品描述：人干扰素诱导T细胞趋化因子(ITAC/CXCL11)酶联免疫试剂盒为双抗夹心法ELISA试剂盒，定量检测血清、血浆、组织匀浆样本中的CXCL11含量。CXCL11，也称为干扰素诱导的T细胞α趋化因子（I-TAC），是一种CXC趋化因子家族的小分子细胞因子。它在多种细胞中表达，如白细胞、成纤维细胞和内皮细胞，在干扰素（IFN）刺激后产生。CXCL11通过结合CXCR3受体发挥其功能，具有趋化性迁移、调节细胞增殖和自我更新、增加细胞粘附和调节血管抑制作用等多效性功能。试剂盒检测范围为31.25 pg/mL-2000 pg/mL，灵敏度为7.8 pg/mL。适用于科研领域研究病毒感染、自身免疫性疾病、肿瘤免疫逃逸等过程中CXCL11的动态表达，或评估靶向趋化因子通路的药物干预效果，为免疫调控机制研究提供可靠工具。本品仅用于科研，不用于临床诊断，产品具体参数及操作步骤详见产品说明书。
别名：b R1 ELISA Kit; b-R1 ELISA Kit; Beta-R1 ELISA Kit; betaR1 ELISA Kit; C-X-C motif chemokine 11 ELISA Kit; Chemokine (C-X-C motif) ligand 11 ELISA Kit; Chemokine C-X-C motif ligand 11 ELISA Kit; CXC11 ELISA Kit; CXCL11 ELISA Kit; CXL11_HUMAN ELISA Kit; H174 ELISA Kit; I TAC ELISA Kit; I-TAC ELISA Kit; Interferon gamma inducible protein 9 ELISA Kit; Interferon gamma-inducible protein 9 ELISA Kit; Interferon inducible T cell alpha chemoattractant ELISA Kit; Interferon-inducible T-cell a chemoattractant I-TAC ELISA Kit; Interferon-inducible T-cell alpha chemoattractant ELISA Kit; IP 9 ELISA Kit; IP-9 ELISA Kit; IP9 ELISA Kit; ITAC ELISA Kit; MGC102770 ELISA Kit; SCYB11 ELISA Kit; SCYB9B ELISA Kit; Small inducible cytokine B11 ELISA Kit; Small inducible cytokine subfamily B (Cys-X-Cys) member 11 ELISA Kit; Small inducible cytokine subfamily B (Cys-X-Cys) member 9B ELISA Kit; Small inducible cytokine subfamily B; member 11 ELISA Kit; Small inducible cytokine subfamily B; member 9B ELISA Kit; Small-inducible cytokine B11 ELISA Kit
缩写：CXCL11
Uniprot No.：O14625
种属：Homo sapiens (Human)
样本类型：serum, plasma, tissue homogenates
检测范围：31.25 pg/mL-2000 pg/mL
灵敏度：7.8 pg/mL
反应时间：1-5h
样本体积：50-100ul
检测波长：450 nm
研究领域：Immunology
测定原理：quantitative
测定方法：Sandwich
精密度：
| Intra-assay Precision (Precision within an assay): CV%<8% | ||||||
| Three samples of known concentration were tested twenty times on one plate to assess. | ||||||
| Inter-assay Precision (Precision between assays): CV%<10% | ||||||
| Three samples of known concentration were tested in twenty assays to assess. | ||||||
线性度：
| To assess the linearity of the assay, samples were spiked with high concentrations of human I-TAC in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay. | ||||||
| Sample | Serum(n=4) | |||||
| 1:1 | Average % | 87 | ||||
| Range % | 81-95 | |||||
| 1:2 | Average % | 96 | ||||
| Range % | 90-105 | |||||
| 1:4 | Average % | 97 | ||||
| Range % | 92-103 | |||||
| 1:8 | Average % | 93 | ||||
| Range % | 86-98 | |||||
回收率：
| The recovery of human I-TAC spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section. | ||||||
| Sample Type | Average % Recovery | Range | ||||
| Serum (n=5) | 95 | 83-99 | ||||
| EDTA plasma (n=4) | 97 | 92-100 | ||||
标准曲线：
| These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed. | ||||||
| pg/mlOD1OD2AverageCorrected 20002.6502.5932.6222.522 10001.7041.6841.6941.594 5000.9640.9820.9730.873 2500.5280.5150.5220.422 1250.3300.3220.3260.226 62.50.2150.2200.2180.118 31.250.1620.1690.1660.066 00.1020.0970.100 | ||||||
货期：3-5 working days
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