关键信息
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基因名
DEFb2
- 应用
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别名
DEFb2；DEFB102；DEFB2；DEFB4；Defensin beta 4A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15263
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表达区间
24-64aa
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氨基酸序列
GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P
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分子量
4.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
DEFb2 is a member of the β-defensin family, which plays a crucial role in the innate immune response of various species, including humans. These small cationic peptides are primarily produced by epithelial cells and possess antimicrobial properties, making them vital for the first line of defense against pathogens. Recent studies have indicated that DEFb2 exhibits not only direct antimicrobial activity but also immunomodulatory effects, influencing the activity of immune cells and participating in wound healing processes. Research on DEFb2 has gained attention due to its potential therapeutic applications, especially in the context of antibiotic resistance and chronic inflammatory diseases. The ability to generate recombinant DEFb2 protein allows for in-depth studies of its functional mechanisms and paves the way for the development of novel antimicrobial agents or immune modulators. Investigating the structural attributes and biological activities of DEFb2 is essential for understanding its role in immunity and for harnessing its potential in clinical settings.
