关键信息
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基因名
MCP3
- 应用
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别名
MCP3；MCP3；SCYA6；SCYA7；C-C motif chemokine 7
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P80098
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表达区间
24-99aa
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氨基酸序列
QPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKE ICADPTQKWVQDFMKHLDKKTQTPKL
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分子量
9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MCP3 recombinant protein, derived from the gene encoding the Monocyte Chemoattractant Protein 3 (MCP-3), has garnered significant attention in immunology and inflammatory research due to its pivotal role in immune responses and inflammation. MCP-3 is a member of the CC chemokine family and is primarily involved in the recruitment of monocytes, T cells, and basophils to sites of inflammation. Its expression is upregulated in various pathological conditions, including autoimmune diseases, cancer, and infections, making it a potential biomarker for disease progression and a target for therapeutic intervention. The production of MCP3 as a recombinant protein allows for detailed studies on its structure, function, and interactions with receptors such as CCR2 and CCR4. Research has demonstrated that MCP-3 can influence the behavior of immune cells, promote angiogenesis, and modulate the inflammatory response, highlighting its importance in both normal physiology and disease pathology. Additionally, understanding the mechanisms through which MCP-3 operates may provide insights into developing novel treatments for inflammatory diseases. Overall, the study of MCP3 recombinant protein is crucial for elucidating the complex interplay of immune signaling pathways and their implications for human health and disease management.
