Cat: PA1000-8064

Recombinant Human FGF11 Protein,His

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关键信息

  • 基因名

    FGF11

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    FGF11;FHF3;Fibroblast growth factor 11

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q92914

  • 表达区间

    1-225aa

  • 氨基酸序列

    MAALASSLIR QKREVREPGG SRPVSAQRRV CPRGTKSLCQ KQLLILLSKV RLCGGRPARP DRGPEPQLKG IVTKLFCRQG FYLQANPDGS IQGTPEDTSS FTHFNLIPVG LRVVTIQSAK LGHYMAMNAE GLLYSSPHFT AECRFKECVF ENYYVLYASA LYRQRRSGRA WYLGLDKEGQ VMKGNRVKKT KAAAHFLPKL LEVAMYQEPS LHSVPEASPS SPPAP

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

Fibroblast growth factor 11 (FGF11) is a member of the FGF family, which plays crucial roles in various biological processes, including development, cellular proliferation, differentiation, and tissue repair. Unlike other FGFs that primarily function through receptor-mediated signaling pathways, FGF11 is unique in that it interacts with intracellular targets rather than cell surface receptors. This distinction highlights its potential significance in intracellular signaling mechanisms, particularly in the nervous system and cardiac tissues. Recent studies suggest that FGF11 may be linked to neurodegenerative diseases and cardiac disorders, underscoring the importance of understanding its molecular functions. The research on recombinant FGF11 protein primarily focuses on its structural and functional properties, which are essential for elucidating its role in health and disease. Advances in recombinant protein technology have enabled the production of FGF11 in sufficient quantities for biochemical and biophysical characterization. This has paved the way for investigating its interactions with other proteins and cellular components, thus laying the groundwork for potential therapeutic applications. Understanding the biological roles and mechanisms of FGF11 through recombinant protein studies could lead to novel insights into its function in pathological conditions and contribute to the development of targeted treatments. The exploration of FGF11 not only expands our knowledge of FGF family members but also provides a valuable framework for investigating similar growth factors and their intricate roles in cellular dynamics.

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