| 经过测试的应用 | |
| 偶联物 | Unconjugated |
| 修饰 | Unmodified |
| 反应物种 | Mouse |
| SwissProt ID | P43432 |
| 抗体类型 | Monoclonal Antibody |
| 克隆性 | Monoclonal |
| 宿主 | Rabbit |
| 基因名 | Il12b |
| 背景信息 | Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of pro-inflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
| 形式 | Liquid |
| 存储缓冲液 | 0.01M PBS, pH 7.2 |
| 储存 | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
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