| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | TMEM71 |
| Uniprot No | Q6P5X7 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-276 aa |
| 活性数据 | MYRISQLMSTPVASSSRLEREYAGELSPTCIFPSFTCDSLDGYHSFECGSIDPLTGSHYTCRRSPRLLTNGYYIWTEDSFLCDKDGNITLNPSQTSVMYKENLVSTSKSWLHGSIFGDINSSPSEDNWLKGTRRLDTDHCNGNADDLDCSSLTDDWESGKMNAESVITSSSSHIISQPPGGNSHSLSLQSQLTASERFQENSSDHSETRLLQEVFFQAILLAVCLIISACARWFMGEILASVFTCSLMITVAYVKSLFLSLASYFKTTACARFVKI |
| 分子量 | 57 kDa |
| 蛋白标签 | 0 |
| 缓冲液 | PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人TMEM71蛋白的3篇参考文献示例(文献信息为虚构，仅供示例参考)：
1. **《TMEM71蛋白在精子发生中的功能研究》**
*作者：Zhang L., et al.*
*摘要*：研究揭示了TMEM71在小鼠精子顶体形成中的关键作用，通过基因敲除实验发现其缺失导致精子形态异常及不育，表明其在哺乳动物生殖细胞发育中的重要性。
2. **《人TMEM71重组蛋白的晶体结构与膜定位分析》**
*作者：Wang Y., Chen H.*
*摘要*：首次解析了重组人TMEM71蛋白的晶体结构，发现其具有跨膜螺旋结构域，并通过细胞实验证明其定位于内质网膜，推测参与跨膜蛋白运输调控。
3. **《TMEM71在胶质母细胞瘤中的异常表达及临床意义》**
*作者：Kim S., et al.*
*摘要*：通过组织样本分析发现TMEM71在胶质母细胞瘤中高表达，并与其恶性程度相关，体外实验显示敲低TMEM71可抑制肿瘤细胞增殖，提示其作为潜在治疗靶点。
**Background of Recombinant Human TMEM71 Protein**
Transmembrane protein 71 (TMEM71) is a poorly characterized protein encoded by the *TMEM71* gene in humans, belonging to the transmembrane protein family. It is predicted to contain multiple transmembrane domains, suggesting a role in membrane-associated processes. While its exact biological functions remain unclear, TMEM71 is speculated to participate in cellular adhesion, signaling, or organelle organization. Bioinformatic analyses indicate potential involvement in developmental processes and tissue homeostasis, with expression detected in brain, testis, and other organs.
Recombinant human TMEM71 protein is engineered using heterologous expression systems (e.g., *E. coli* or mammalian cells) for functional studies. Its recombinant form allows researchers to investigate interactions, localization, and activity in vitro or in cell-based assays. Current research focuses on elucidating its role in diseases, such as cancer or neurological disorders, where altered TMEM71 expression has been observed. However, mechanistic insights remain limited, highlighting the need for further exploration.
As a research tool, recombinant TMEM71 serves as an antigen for antibody development, a substrate for binding assays, or a target for pathway analysis. Its study could uncover novel therapeutic targets or biomarkers. Despite its enigmatic nature, TMEM71 represents an intriguing subject for unraveling membrane protein biology and disease pathophysiology.
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