关键信息
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基因名
CCNDBP1
- 应用
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别名
AU022347; CCDB1_HUMAN; CCNDBP 1; Ccndbp1; Cyclin D type binding Protein 1; Cyclin-D1-binding Protein 1; D type cyclin interacting Protein 1; DIP 1; DIP1; GCIP; Grap 2 and cyclin D interacting Protein; Grap 2 cyclin D interacting Protein GCIP
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O95273
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表达区间
1-360aa
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氨基酸序列
MASATAPAAAVPTLASPLEQLRHLAEELRLLLPRVRVGEAQETTEEFNREMFWRRLNEAAVTVSREATTLTIVFSQLPLPSPQETQKFCEQVHAAIKAFIAVYYLLPKDQGITLRKLVRGATLDIVDGMAQLMEVLSVTPTQSPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLTKNVDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQDLYWSEDDQELIIPCLALVRASKACLKKIRMLVAENGKKDQVAQLDDIVDISDEISPSVDDLALSIYPPMCHLTVRINSAKLVSVLKKALEITKASHVTPQPEDSWIPLLINAIDHCMNRIKELTQSELEL
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分子量
66.7 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CCNDBP1, or CCN domain-binding protein 1, is a member of the CCN (connective tissue growth factor, cysteine-rich protein 61, and Nov) family of proteins, which are known for their roles in cell proliferation, differentiation, and extracellular matrix regulation. Research has shown that CCNDBP1 is implicated in various cellular processes, including regulation of gene expression and cellular signaling pathways, and is associated with several physiological and pathological conditions, such as tissue repair and cancer progression. The protein has garnered interest due to its potential as a biomarker for certain diseases as well as its significance in understanding cell behavior in development and disease contexts. Despite its functional importance, studies on CCNDBP1 have been limited by the lack of sufficient quantities of the protein for detailed biochemical analyses. Therefore, recombinant expression of CCNDBP1 in suitable host organisms, such as bacteria or eukaryotic cells, represents a promising approach to producing this protein at scale. This methodology can facilitate the study of CCNDBP1's structure, function, and interactions, thereby advancing our understanding of its role in health and disease. Consequently, the research on the recombinant protein provides essential insights that can lead to therapeutic advancements, making CCNDBP1 a significant focus in the field of molecular biology and cancer research.
