关键信息
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基因名
REEP5
- 应用
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别名
Receptor expression-enhancing protein 5. Polyposis locus protein 1. Protein TB2
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q00765
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表达区间
1-185 aa
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氨基酸序列
MRERFDRFLHEKNCMTDLLAKLEAKTGVNRSFIALGVIGLVALYLVFGYGASLLCNLIGFGYPAYISIKAIESPNKEDDTQWLTYWVVYGVFSIAEFFSDIFLSWFPFYYMLKCGFLLWCMAPSPSNGAELLYKRIIRPFFLKHESQMDSVVKDLKDKAKETADAITKEAKKATVNLLGEEKKST
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分子量
47.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
REEP5, a member of the REEP (Receptor Expression Enhancer Protein) family, has garnered significant interest in recent years due to its potential roles in various cellular processes, including protein trafficking and membrane dynamics. Initially identified as a factor influencing G protein-coupled receptor (GPCR) expression, REEP5 has been implicated in the modulation of receptor signaling pathways, impacting physiological responses such as neurotransmission and hormone signaling. Its unique ability to interact with cellular membranes suggests that REEP5 may play a crucial role in shaping organelle morphology and function, particularly in the endoplasmic reticulum (ER). Dysregulation of REEP5 has been linked to various diseases, including certain neurodegenerative disorders and cancers, highlighting its significance as a potential biomarker or therapeutic target. Furthermore, studies have demonstrated that REEP5 can affect the stability and localization of its interactors, providing insights into its mechanistic functions in cellular homeostasis. Given its multifaceted roles, ongoing research into the structure and function of REEP5, particularly its recombinant forms, is essential for elucidating its contributions to cellular physiology and pathophysiology, paving the way for novel interventions in relevant diseases.
