关键信息
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基因名
C19orf46
- 应用
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别名
SYNE4; C19orf46; Nesprin-4; KASH domain-containing Protein 4; KASH4; Nuclear envelope spectrin repeat Protein 4
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8N205
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表达区间
1-291aa
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氨基酸序列
MALSLPLGPRLGSEPLNHPPGAPREADIVGCTVCPASGEESTSPEQAQTLGQDSLGPPEHFQGGPRGNEPAAHPPRWSTPSSYEDPAGGKHCEVFEEANTLDQDLEVEGDSDWPGPGGVWGPWAPSSLPTSTELEWDPAGDIGGLGPLGQKTARTLGVPCELCGHRGPQGRGQGLEEADTSHSRQDMLESGLGHQKRLARHQRHSLLRKPQDKKRQASPHLQDVRLEGNPGAPDPASRQPLTFLLILFLLFLLLVGAMFLLPASGGPCCSHARIPRTPYLVLSYVNGLPPV
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分子量
57.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
C19orf46, also known as "chromosome 19 open reading frame 46," is a gene located on chromosome 19 that has garnered interest in recent years due to its potential implications in cellular processes and disease mechanisms. Recent studies suggest that C19orf46 may play a crucial role in cellular growth, differentiation, and apoptosis, which are essential for maintaining tissue homeostasis and functionality. Despite its growing prominence in biomedical research, the specific biological functions of C19orf46 remain largely unexplored. The recombinant protein of C19orf46 is being investigated as a means to better understand its structure and function, with the aim of elucidating its role in various physiological and pathological contexts, such as cancer and neurodegenerative diseases. Researchers are focused on producing high-quality recombinant C19orf46 to analyze its interactions, localization, and effects on cellular pathways. This will help to clarify its putative involvement in signaling networks and provide insights into how its dysregulation could lead to disease. Further investigation into the recombinant C19orf46 protein is expected to shed light on its biological significance and potentially identify it as a novel therapeutic target or biomarker for various diseases.
