关键信息
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基因名
PTRH1
- 应用
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别名
PTRH1; C9orf115; Probable peptidyl-tRNA hydrolase; PTH; EC 3.1.1.29
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q86Y79
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表达区间
1-214 aa
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氨基酸序列
MRPGGFLGAG QRLSRAMSRC VLEPRPPGKR WMVAGLGNPG LPGTRHSVGM AVLGQLARRL GVAESWTRDR HCAADLALAP LGDAQLVLLR PRRLMNANGR SVARAAELFG LTAEEVYLVH DELDKPLGRL ALKLGGSARG HNGVRSCISC LNSNAMPRLR VGIGRPAHPE AVQAHVLGCF SPAEQELLPL LLDRATDLIL DHIRERSQGP SLGP
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分子量
22.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
PTRH1, or peptide transferase-related homolog 1, is a protein that plays a significant role in various cellular processes, including protein synthesis and stress response. Research into PTRH1 has been prompted by its potential involvement in regulating translational control and its implications in various diseases, including cancer and neurodegenerative disorders. As a functional homolog of the human peptide transferase, PTRH1 is believed to interact with ribosomes, influencing the rate of protein synthesis and ensuring proper cellular function under stress conditions. Furthermore, studies have shown that aberrations in PTRH1 expression can affect cell viability and proliferation, making it an attractive target for therapeutic interventions. The exploration of PTRH1's structure and function not only enhances our understanding of molecular biology but also underscores its potential as a biomarker for disease progression and response to treatment. By investigating PTRH1's role in these critical pathways, researchers aim to uncover new strategies for managing diseases characterized by dysregulated protein synthesis and cellular stress responses.
