| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | NYREN18 |
| Uniprot No | Q9Y5A7 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-615 aa |
| 活性数据 | MAQKKYLQAK LTQFLREDRI QLWKPPYTDE NKKVGLALKD LAKQYSDRLE CCENEVEKVI EEIRCKAIER GTGNDNYRTT GIATIEVFLP PRLKKDRKNL LETRLHITGR ELRSKIAETF GLQENYIKIV INKKQLQLGK TLEEQGVAHN VKAMVLELKQ SEEDARKNFQ LEEEEQNEAK LKEKQIQRTK RGLEILAKRA AETVVDPEMT PYLDIANQTG RSIRIPPSER KALMLAMGYH EKGRAFLKRK EYGIALPCLL DADKYFCECC RELLDTVDNY AVLQLDIVWC YFRLEQLECL DDAEKKLNLA QKCFKNCYGE NHQRLVHIKG NCGKEKVLFL RLYLLQGIRN YHSGNDVEAY EYLNKARQLF KELYIDPSKV DNLLQLGFTA QEARLGLRAC DGNVDHAATH ITNRREELAQ IRKEEKEKKR RRLENIRFLK GMGYSTHAAQ QVLHAASGNL DEALKILLSN PQMWWLNDSN PETDNRQESP SQENIDRLVY MGFDALVAEA ALRVFRGNVQ LAAQTLAHNG GSLPPELPLS PEDSLSPPAT SPSDSAGTSS ASTDEDMETE AVNEILEDIP EHEEDYLDST LEDEEIIIAE YLSYVENRKS ATKKN |
| 分子量 | 70.5 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是基于假设虚构的关于“重组人NYREN18蛋白”的示例参考文献(实际应用中请替换为真实文献)：
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1. **文献名称**：Structural Characterization and Functional Analysis of Recombinant Human NYREN18 Protein
**作者**：Smith J, Wang L, et al.
**摘要**：本研究成功表达并纯化了重组人NYREN18蛋白，通过X射线晶体学解析其三维结构，发现其具有独特的底物结合域。功能实验表明，该蛋白在体外可调节细胞内钙离子信号通路，可能与神经退行性疾病相关。
2. **文献名称**：NYREN18 Recombinant Protein Promotes Angiogenesis in Ischemic Models
**作者**：Chen H, Kimura T, et al.
**摘要**：本文报道重组人NYREN18蛋白在缺血小鼠模型中显著增强血管生成，其机制可能通过激活VEGF通路实现，提示其在心血管疾病治疗中的潜在应用价值。
3. **文献名称**：The Role of Recombinant NYREN18 in Immune Regulation: Insights from In Vitro Studies
**作者**：Rodriguez M, Gupta S, et al.
**摘要**：研究利用重组NYREN18蛋白处理免疫细胞，发现其抑制Th17细胞分化并促进Treg细胞增殖，表明其对自身免疫疾病(如多发性硬化症)具有免疫调节作用。
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**备注**：以上文献均为示例性质，“NYREN18”名称可能不真实，建议通过PubMed、Google Scholar等平台，以“NYREN18”或相关基因名(如确认)结合关键词检索真实文献。
**Background of Recombinant Human NYREN18 Protein**
Recombinant human NYREN18 protein is a genetically engineered protein derived from the human NYREN18 gene, which encodes a poorly characterized protein implicated in various cellular processes. NYREN18 was initially identified through bioinformatic analyses of human genomic data, with its name reflecting its discovery in specific cancer-related studies (e.g., "NY" denoting hypothetical tumor-associated antigens). The protein is hypothesized to play roles in cell signaling, differentiation, or immune regulation, though its exact mechanisms remain under investigation.
Recombinant NYREN18 is typically produced using expression systems like *E. coli* or mammalian cell cultures, enabling high-purity yields for research applications. Its recombinant form allows precise study of its biochemical properties, interactions, and potential therapeutic relevance. Studies suggest NYREN18 may be overexpressed in certain cancers, linking it to tumor progression or immune evasion, making it a candidate for diagnostic biomarkers or immunotherapy targets.
Current research focuses on elucidating its structure-function relationships, post-translational modifications, and involvement in pathways such as apoptosis or cytokine signaling. Challenges include clarifying its physiological role in healthy tissues versus pathological contexts. Further exploration of NYREN18 could advance understanding of cancer biology and contribute to developing targeted therapies or diagnostic tools.
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