Cat: PA1000-5056

Recombinant Human BIN2 Protein,His

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关键信息

  • 基因名

    BIN2

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    BIN2;BRAP1;Bridging integrator 2

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9UBW5

  • 表达区间

    1-244aa

  • 氨基酸序列

    MAEGKAGGAAGLFAKQVQKKFSRAQEKVLQKLGKAVETKDERFEQSASNF YQQQAEGHKLYKDLKNFLSAVKVMHESSKRVSETLQEIYSSEWDGHEELK AIVWNNDLLWEDYEEKLADQAVRTMEIYVAQFSEIKERIAKRGRKLVDYD SARHHLEAVQNAKKKDEAKTAKAEEEFNKAQTVFEDLNQELLEELPILYN SRIGCYVTIFQNISNLRDVFYREMSKLNHNLYEVMSKLEKQHSN

  • 分子量

    30 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

BIN2 (BRASSINOSTEROID INSENSITIVE 2) is a key component of the brassinosteroid signaling pathway, primarily known for its role in plant growth and development. It is a member of the group of proteins that function as negative regulators of brassinosteroid responses. The study of BIN2 is particularly significant due to its involvement in various physiological processes, such as cell elongation, vascular development, and stress response. Researchers have identified that BIN2 interacts with various transcription factors and other signaling proteins, making it a central player in diverse signaling pathways. Understanding the molecular mechanisms behind BIN2 function can provide insights into how plants adapt to environmental stresses and regulate their growth in response to hormonal signals. Moreover, the functional characterization of BIN2 and its signaling interactions can offer potential applications in agricultural biotechnology, particularly in improving crop resilience and yield. Recent studies utilizing recombinant BIN2 proteins have uncovered intricate regulatory networks and have prompted further investigation into the potential for manipulating this pathway in crop improvement strategies. As a result, BIN2 research continues to be a crucial field of study in plant molecular biology, aiming to elucidate the complex signaling mechanisms that govern plant adaptation and development.

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