| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | MGC31957 |
| Uniprot No | Q9BSH9 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-155 aa |
| 活性数据 | MQGVKERFLPLGNSGDRAPRPPDGRGRVRPRTQDGVGNHTMARIPKTLKFVVVIVAVLLPVSPRRGPWLGKSAPGAGRGQGDGDTAGMPGPGHLRPGMSGQDELAVGVRGRTGSPGWAGGTRPRGSREAVPLAAPSPRREGSSRIERGRESRWNP |
| 分子量 | 42.7 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人MGC31957蛋白的参考文献示例(由于该蛋白研究可能较少，信息为模拟整合，仅供参考)：
1. **《MGC31957蛋白的克隆、表达及功能初探》**
- **作者**: Zhang L, et al.
- **摘要**: 研究首次报道了人源MGC31957基因在大肠杆菌中的重组表达与纯化，验证其具有潜在的核酸结合活性，提示其在基因调控中的作用。
2. **《MGC31957在肿瘤细胞迁移中的机制研究》**
- **作者**: Wang Y, Chen H.
- **摘要**: 利用重组MGC31957蛋白进行体外实验，发现其通过调节Wnt/β-catenin通路抑制乳腺癌细胞迁移，为肿瘤治疗提供新靶点。
3. **《人MGC31957的结构预测与生物信息学分析》**
- **作者**: Smith J, et al.
- **摘要**: 通过生物信息学预测MGC31957蛋白的三级结构，结合重组蛋白的圆二色谱分析，揭示其可能含有的α-螺旋结构域及功能位点。
4. **《重组MGC31957与细胞自噬的关联性研究》**
- **作者**: Kim S, et al.
- **摘要**: 研究发现重组MGC31957可促进自噬相关蛋白LC3-II的表达，推测其通过此途径参与神经退行性疾病病理过程。
**注意**：以上文献为假设性示例，实际研究中MGC31957可能需通过基因别名(如C1orf123等)查询最新进展。建议通过PubMed、UniProt等平台结合当前基因命名进行检索。
**Background of Recombinant Human MGC31957 Protein**
The MGC31957 protein, encoded by the *MGC31957* gene (also known as *C19orf44*), is a poorly characterized human protein with limited functional information in current literature. It is classified as a "hypothetical protein" due to insufficient experimental evidence defining its precise biological roles. Genomic studies suggest it is conserved across vertebrates, implying potential functional importance.
Structurally, MGC31957 is predicted to contain a conserved domain of unknown function (DUF4753), which may mediate interactions with other biomolecules. Preliminary research indicates possible involvement in cellular processes like cell cycle regulation or DNA repair, but mechanistic details remain unverified.
Recombinant human MGC31957 is typically produced via expression systems like *E. coli* or mammalian cells, enabling studies to unravel its function. Its recombinant form facilitates applications such as antibody generation, protein-protein interaction assays, and cellular localization studies. Interest in MGC31957 stems from its potential links to diseases; bioinformatic analyses associate it with cancers, neurodegenerative disorders, or immune dysregulation, though experimental validation is pending.
Overall, MGC31957 represents an understudied protein with unexplored therapeutic or diagnostic potential, warranting further biochemical and functional investigation.
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