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Recombinant Human MGC24039 Protein

  • 中文名: 重组人(MGC24039)蛋白
  • 别    名: DENN domain containing 5B
货号: PA2000-9302
Price: ¥询价
数量:
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产品详情

纯度>90%SDS-PAGE.
种属Human
靶点MGC24039
Uniprot NoG3V1S3
内毒素< 0.01EU/μg
表达宿主E.coli
表达区间1-507 aa
活性数据MLCMPKGLSFRTQTDNKDPQFHSFIITREDGSRTYGFVLTFYEEVTSKQICTAMQTLYQMHNAEHYSSVYASSSCSMDSLASSLDEGDTTSLLKLQRYNSYDISRDTLYVSKSICLITPLPFMQACKKFLIQLYKAVTSQQPPPLPLESYIHNILYEVPLPPPGRSLKFYGVYEPVICQRPGPSELPLSDYPLREAFELLGLENLVQVFTCVLLEMQILLYSQDYQRLMTVAEGITTLLFPFQWQHVYVPILPASLLHFLDAPVPYLMGLQSKEGTDRSKLELPQEANLCFVDIDNHFIELPEEFPQFPNKVDFIQELSEVLVQFGIPPEGSLHCSESTSKLKNMVLKDLVNDKKNGNVCTNNISMYELLKGNETIARLQALAKRTGVAVEKMDLSASLGEKDKDLKLHCEEAELRDYQLNVQLREVFANRFTQMFADYEAFVIQTAQDMESWLTNREQMQNFDKVKRTIVFLLWLLVALLLILTFLNFLFFCAYAYPYIIDFVNLF
分子量81.51 kDa
蛋白标签GST-tag at N-terminal
缓冲液0
稳定性 & 储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
复溶Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

参考文献

以下是关于重组人MGC24039蛋白的3篇模拟参考文献示例(注意:这些文献为假设示例,实际检索可能需要结合具体数据库和最新研究):

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1. **文献名称**: *"Recombinant Expression and Functional Analysis of Human MGC24039 in a Prokaryotic System"*

**作者**: Zhang, L. et al.

**摘要**: 该研究报道了在大肠杆菌中成功表达并纯化重组人MGC24039蛋白,验证其通过调控MAPK信号通路影响肿瘤细胞增殖的功能。

2. **文献名称**: *"Structural Insights into MGC24039: A Novel Player in Neuronal Development"*

**作者**: Yamamoto, K. et al.

**摘要**: 利用昆虫细胞系统表达重组MGC24039.结合冷冻电镜技术解析其三维结构,揭示其独特的结构域可能参与神经元突触形成的分子机制。

3. **文献名称**: *"MGC24039 as a Potential Biomarker in Inflammatory Diseases: Evidence from Recombinant Protein-based Assays"*

**作者**: Smith, J. et al.

**摘要**: 通过哺乳动物细胞(HEK293)表达带有标签的重组MGC24039蛋白,发现其与炎症因子IL-6的相互作用,提示其在自身免疫疾病中的潜在作用。

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**注意**:以上文献为模拟内容,实际研究中建议通过 **PubMed**、**Google Scholar** 或 **UniProt数据库(检索编号可能存在别名,如“C14orf105”)** 获取最新进展。若需具体实验细节,可补充蛋白的别称或相关通路进一步检索。


背景信息

**Background of Recombinant Human MGC24039 Protein**

The recombinant human MGC24039 protein is a less-characterized protein encoded by the *MGC24039* gene, also known as *C16orf89*, located on chromosome 16. While its precise biological function remains unclear, studies suggest it may play roles in cellular processes such as protein-protein interactions or signaling pathways. Structural predictions indicate potential transmembrane domains or motifs involved in subcellular localization, though experimental validation is limited.

As a recombinant protein, MGC24039 is typically expressed in heterologous systems (e.g., *E. coli*, HEK293. or insect cells) with engineered tags (e.g., His, GST) to facilitate purification and detection. This enables its use in functional studies, antibody development, or screening assays. Its low abundance in native tissues and limited literature highlight its status as a "hypothetical" or understudied protein, often categorized under poorly annotated genes in genomic databases.

Current research focuses on elucidating its interactome, tissue-specific expression patterns, and potential links to diseases. Recombinant MGC24039 serves as a critical tool for unraveling its physiological or pathological relevance, particularly in cancer or metabolic disorders where chromosome 16 alterations are observed. Further characterization may uncover novel therapeutic targets or biomarkers.

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