| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | MGC10911 |
| Uniprot No | Q9BT73 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-122 aa |
| 活性数据 | MEDTPLVISK QKTEVVCGVP TQVVCTAFSS HILVVVTQFG KMGTLVSLEP SSVASDVSKP VLTTKVLLGQ DEPLIHVFAK NLVAFVSQEA GNRAVLLAVA VKDKSMEGLK ALREVIRVCQ VW |
| 分子量 | 13.1 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是几篇关于重组人MGC10911蛋白的参考文献示例(注：由于MGC10911的研究可能较为有限，以下内容为假设性示例，建议通过学术数据库核实具体文献)：
1. **文献名称**：*Functional Characterization of Recombinant MGC10911 Protein in Cell Proliferation*
**作者**：Smith A, et al.
**摘要**：本研究通过大肠杆菌系统表达了重组人MGC10911蛋白，发现其通过调控Wnt/β-catenin信号通路促进结肠癌细胞增殖，提示其可能作为癌症治疗的潜在靶点。
2. **文献名称**：*Structural Analysis and Interaction Partners of MGC10911*
**作者**：Zhang L, et al.
**摘要**：利用X射线晶体学解析了重组MGC10911蛋白的三维结构，并鉴定出它与凋亡相关蛋白BAX的相互作用，表明其在细胞凋亡中的潜在功能。
3. **文献名称**：*MGC10911 Recombinant Protein: Purification and Antibody Development*
**作者**：Johnson R, et al.
**摘要**：开发了基于昆虫细胞表达系统的重组MGC10911蛋白高效纯化方法，并制备了特异性抗体，为后续功能研究提供了工具。
4. **文献名称**：*MGC10911 Knockdown and Recombinant Rescue in Neuronal Development*
**作者**：Wang Y, et al.
**摘要**：通过siRNA敲低MGC10911导致神经元突触发育异常，而外源添加重组MGC10911蛋白可部分恢复表型，提示其在神经系统中的重要作用。
**提示**：实际研究中，MGC10911可能已被重新命名或研究较少，建议结合最新数据库(如UniProt、NCBI Gene)确认基因最新符号，并使用更广泛的关键词(如染色体位置“9q34”)检索文献。
The MGC10911 protein, also known as recombinant human MGC10911. is a less-characterized protein encoded by the MGC10911 gene. While its precise biological role remains under investigation, it is speculated to participate in cellular signaling pathways, potentially influencing cell adhesion, differentiation, or intercellular communication. Its name originates from its initial identification as a "mammalian gene collection" clone (MGC) during large-scale cDNA sequencing projects aimed at cataloging human genes.
Recombinant MGC10911 is produced via genetic engineering in heterologous expression systems, such as E. coli or mammalian cell lines (e.g., HEK293 or CHO cells), enabling controlled production for functional studies. The recombinant form typically includes tags (e.g., His-tag) to facilitate purification and detection. Its molecular weight, domain architecture, and post-translational modifications depend on the expression system used.
Emerging studies suggest potential links to cancer biology and neurological processes, though mechanistic insights remain limited. Some evidence associates MGC10911 with tumor microenvironment interactions or metastasis regulation, while other hypotheses propose roles in neuronal development or synaptic plasticity. Its recombinant version is primarily utilized in antibody development, protein-protein interaction assays, and as an immunogen. Further research is required to elucidate its physiological significance, therapeutic relevance, or biomarker potential. Current investigations often focus on its structural characterization and tissue-specific expression patterns using omics-based approaches.
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