| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LYZL2 |
| Uniprot No | Q7Z4W2 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-194aa |
| 活性数据 | MQDAPLSCLSPTKWSSVSSADSTEKSASAAGTRNLPFQFCLRQALRMKAAGILTLIGCLVTGAESKIYTRCKLAKIFSRAGLDNYWGFSLGNWICMAYYESGYNTTAQTVLDDGSIDYGIFQINSFAWCRRGKLKENNHCHVACSALVTDDLTDAIICAKKIVKETQGMNYWQGWKKHCEGRDLSDWKKDCEVS |
| 分子量 | 48 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人LYZL2蛋白的3篇参考文献的示例(注：以下文献信息为模拟生成，可能不存在真实对应文献，仅供格式参考)：
1. **文献名称**: *"Expression and Characterization of Recombinant Human LYZL2 Protein in Escherichia coli"*
**作者**: Zhang, Y. et al.
**摘要**: 本研究通过大肠杆菌系统成功表达并纯化了重组人LYZL2蛋白，验证其具有溶菌酶样结构域及水解细菌细胞壁的酶活性，提示其可能在先天免疫中发挥作用。
2. **文献名称**: *"LYZL2: A Novel Sperm-Associated Protein with Potential Role in Male Fertility"*
**作者**: Wang, H. & Chen, L.
**摘要**: 通过质谱分析发现LYZL2蛋白特异性表达于人类精子顶体区域，重组LYZL2可促进精子穿透卵子透明带，其异常表达可能与男性不育相关。
3. **文献名称**: *"Structural Insights into the Antimicrobial Mechanism of Human LYZL2 Protein"*
**作者**: Kim, S. et al.
**摘要**: 解析了重组LYZL2的晶体结构，揭示其通过结合革兰氏阳性菌细胞壁肽聚糖发挥抗菌活性，为开发新型抗菌药物提供理论依据。
如需真实文献，建议通过PubMed或Web of Science检索关键词 **"LYZL2 recombinant protein"** 或 **"LYZL2 function"**。
Recombinant human LYZL2 protein is a genetically engineered form of the Lysozyme-like protein 2 (LYZL2), a member of the lysozyme superfamily. Lysozymes are enzymes traditionally known for hydrolyzing bacterial cell walls, but LYZL2 exhibits distinct tissue-specific roles. Primarily expressed in the male reproductive system, particularly in the epididymis and testes, LYZL2 is implicated in sperm maturation, fertilization, and innate immune defense within the urogenital tract. The protein contains conserved structural motifs, including a glycohydrolase domain at the N-terminus and a cysteine-rich region at the C-terminus, suggesting dual functionality in substrate binding and enzymatic activity.
Research indicates that LYZL2 may contribute to sperm surface remodeling by modifying glycoproteins, potentially influencing sperm motility and egg-binding capacity. Dysregulation of LYZL2 has been linked to male infertility, epididymal inflammation, and prostate cancer progression, highlighting its clinical relevance. Recombinant LYZL2 is produced using *in vitro* expression systems (e.g., E. coli or mammalian cells) to study its biochemical properties, molecular interactions, and therapeutic potential. This protein serves as a tool to investigate mechanisms of sperm-egg interaction, antimicrobial activity in reproductive tissues, and as a biomarker for diagnosing reproductive disorders. Its recombinant form enables controlled studies to explore enzyme kinetics, structural biology, and possible applications in fertility treatments or anti-infective therapies.
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