| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LUZP4 |
| Uniprot No | Q9P127 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-313aa |
| 活性数据 | MASFRKLTLSEKVPPNHPSRKKVNFLDMSLDDIIIYKELEGTNAEEEKNKRQNHSKKESPSRQQSKAHRHRHRRDYSRCRSNSEEGNHDKKPSQKPSGFKSGQHPLNGQPLIEQEKCSDNYEAQAEKNQGQSEGNQHQSEGNPDKSEESQGQPEENHHSERSRNHLERSLSQSDRSQGQLKRHHPQYERSHGQYKRSHGQSERSHGHSERSHGHSERSHGHSERSHGHSKRSRSQGDLVDTQSDLIATQRDLIATQKDLIATQRDLIATQRDLIVTQRDLVATERDLINQSGRSHGQSERHQRYSTGKNTITT |
| 分子量 | 60.83 KDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人LUZP4蛋白的假设性参考文献示例(请注意，以下信息为模拟生成，实际文献可能需要进一步验证)：
1. **文献名称**：*LUZP4在细胞分裂中的功能与调控机制研究*
**作者**：Smith J, Lee K, et al.
**摘要**：本研究通过重组表达人LUZP4蛋白，揭示了其通过与中心体蛋白相互作用调控有丝分裂的机制，并发现其异常表达可能导致染色体分离错误。
2. **文献名称**：*重组人LUZP4的纯化及其在神经发育中的作用*
**作者**：Zhang Y, Wang M, et al.
**摘要**：利用大肠杆菌系统重组表达并纯化LUZP4蛋白，发现其促进神经元轴突延伸，并通过RNA干扰实验验证了其在神经突触形成中的关键作用。
3. **文献名称**：*LUZP4与癌症转移的关联：基于重组蛋白的功能分析*
**作者**：Garcia R, Tanaka S, et al.
**摘要**：通过重组人LUZP4蛋白的体外实验，证实其抑制上皮-间质转化(EMT)的能力，低表达可能促进肿瘤细胞的侵袭和转移。
4. **文献名称**：*人LUZP4蛋白的晶体结构解析及其相互作用界面研究*
**作者**：Chen L, Müller U, et al.
**摘要**：利用重组表达的LUZP4蛋白进行X射线晶体学分析，首次报道了其三维结构，并鉴定出与微管结合相关的关键结构域。
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**注意**：上述文献为示例性质，实际研究中建议通过PubMed、Google Scholar等平台检索最新文献，并以真实数据为准。LUZP4相关研究可能较为前沿或有限，可尝试扩展关键词(如“Leucine zipper protein 4”)进行搜索。
LuzP4 (leucine zipper protein 4) is a poorly characterized human protein encoded by the *LUZP4* gene. It belongs to the leucine zipper protein family, defined by conserved alpha-helical domains rich in leucine residues that mediate protein-protein interactions, often involved in transcriptional regulation or signaling pathways. Though its exact biological role remains unclear, LUZP4 is speculated to participate in cellular processes such as cell cycle control, apoptosis, or cytoskeletal organization based on structural homology to related proteins.
Recombinant human LUZP4 protein is produced using expression systems (e.g., *E. coli* or mammalian cells) for in vitro studies. Its recombinant form enables researchers to explore its biochemical properties, interactions, and potential involvement in diseases. Limited studies suggest LUZP4 may interact with components of the ubiquitin-proteasome system or nuclear transport machinery, but functional validation is ongoing. Interest in LUZP4 also stems from its genomic location near cancer-associated loci and possible links to developmental disorders. However, comprehensive mechanistic insights are lacking, highlighting the need for further research using tools like recombinant LUZP4 to clarify its physiological and pathological roles, structural motifs, and therapeutic potential. Current applications focus on antibody development, protein interaction mapping, and disease biomarker discovery.
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