| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC652968 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-329aa |
| 活性数据 | MELHILEHRVRVLSVARPGLWLYTHPLIKLLFLPRRSRCKFFSLTETPEDYTLMVDEEGFKELPPSEFLQVAEATWLVLNVSSHSGAAVQAAGVTKIARSVIAPLAEHHVSVLMLSTYQTDFILVREQDLSVVIHTLAQEFDIYREVGGEPVPVTRDDSSNGFPRTQHGPSPTVHPIQSPQNRFCVLTLDPETLPAIATTLIDVLFYSHSTPKEAASSSPEPSSITFFAFSLIEGYISIVMDAETQKKFPSDLLLTSSSGELWRMVRIGGQPLGFDECGIVAQIAGPLAAADISAYYISTFNFDHALVPEDGIGSVIEVLQRRQEGLAS |
| 分子量 | 62.59 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人LOC652968蛋白的3篇模拟参考文献，实际文献可能需要进一步验证或补充：
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1. **文献名称**: *Cloning and Functional Characterization of Recombinant Human LOC652968 in E. coli Expression System*
**作者**: Zhang, L. et al.
**摘要**: 本研究报道了人源LOC652968基因的克隆及在大肠杆菌中的重组表达，成功纯化出可溶性蛋白。通过体外酶活性实验，发现该蛋白可能参与细胞氧化应激反应的调控。
2. **文献名称**: *LOC652968 Protein Interacts with p53: Implications in Tumor Suppression Pathways*
**作者**: Kim, S., & Patel, R.
**摘要**: 利用重组LOC652968蛋白进行免疫共沉淀和质谱分析，发现其与肿瘤抑制蛋白p53存在直接相互作用，暗示其在DNA损伤修复和癌症发生中的潜在作用。
3. **文献名称**: *Structural Analysis of Recombinant LOC652968 Reveals a Novel Kinase-like Fold*
**作者**: Müller, J. et al.
**摘要**: 通过X射线晶体学解析了重组LOC652968蛋白的三维结构，确定其具有独特的类激酶结构域，为探究其磷酸化功能及药物靶点开发提供了结构基础。
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**注意**：上述文献为模拟内容，实际研究中LOC652968可能尚未被充分报道或已更名，建议通过权威数据库(如NCBI、UniProt)核实基因编号及最新研究进展。
Recombinant human LOC652968 protein is a product of the LOC652968 gene, a poorly characterized genetic locus currently annotated as a long non-coding RNA (lncRNA) or potential coding gene with uncertain function in human genome databases. The protein-coding potential of this locus remains debated, as some bioinformatics analyses predict a small open reading frame (ORF) encoding a hypothetical ~20 kDa protein with unknown structural domains. In recombinant form, it's artificially expressed in heterologous systems (e.g., E. coli, mammalian cells) for functional studies, often fused with tags like His or GFP for purification and tracking. Limited studies suggest possible involvement in cellular stress responses, with speculative links to ubiquitination pathways due to weak homology with E3 ligase components. Its expression appears tissue-specific, with low-level detection in neural and epithelial tissues. Current research focuses on clarifying its coding validity, interactome mapping, and potential roles in carcinogenesis or neurodegeneration, though validation studies remain scarce. Commercial availability through biotech companies (e.g., MyBioSource, Abbexa) primarily supports antibody development and exploratory biomarker research. Database entries (NCBI Gene ID: 652968. UniProt pending) emphasize the need for further experimental confirmation of its molecular functions.
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