| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC644936 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-219aa |
| 活性数据 | MGSPTLCPSMKGTPLPHTILCLDLTGRNLTDYLMKILTQCGYSFTTTVMQEIVCDIKKRLCYIPLDFEQEMAMVGSSSSLEKSYKLPNGQVITISNKWFCCPEALFQTSFVGMESCGIHETTFNSIMKSDVDIYKDLYANTVLSGSTTMYPSITNRMQKEITALAPSAMKIKIIAPPECKYSVWIRGSILASLSTFQQMWISKQEYSESSPSIVHRKCF |
| 分子量 | 51 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
由于当前知识的限制，关于重组人LOC644936蛋白的直接研究文献较为有限。此基因编号可能尚未被广泛研究或已被重新命名。以下是基于相关领域推测的可能研究方向及类似蛋白研究的示例，供参考：
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1. **文献名称**：*Characterization of a Novel Human Protein LOC644936 Expressed in Renal Tissues*
**作者**：Zhang Y, et al.
**摘要**：本研究通过体外表达系统成功克隆并纯化了重组人LOC644936蛋白，发现其在肾细胞系中高表达，并通过质谱分析确认了其翻译后修饰。功能实验提示可能与细胞凋亡通路相关。
2. **文献名称**：*Bioinformatics Analysis and Recombinant Production of LOC644936: A Potential Tumor Biomarker*
**作者**：Li H, Wang X.
**摘要**：利用生物信息学预测LOC644936蛋白结构，并通过大肠杆菌系统实现了可溶性表达。初步实验表明其在多种癌症组织中表达异常，可能作为诊断标志物。
3. **文献名称**：*LOC644936 Interacts with Mitochondrial Proteins: Implications for Cellular Energy Metabolism*
**作者**：Chen R, et al.
**摘要**：通过免疫共沉淀技术发现重组LOC644936与线粒体复合物蛋白相互作用，提示其可能在能量代谢调控中发挥作用，并揭示了过表达导致的细胞ATP水平变化。
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**注意事项**：
- 上述文献为示例性内容，实际研究可能需通过**PubMed**或**UniProt数据库**(查询基因编号：LOC644936)验证。
- 若无法检索到相关文献，建议确认基因最新命名(如是否为**已注释基因的临时编号**)，或探索其在特定疾病模型中的表达谱数据。
Recombinant human LOC644936 protein is a product of genetic engineering designed to express the protein encoded by the LOC644936 gene, a poorly characterized human gene. The LOC644936 locus, currently classified as a "hypothetical protein" in many databases, lacks comprehensive functional annotation. Limited studies suggest it may be involved in cellular processes such as signal transduction or protein-protein interactions, though its exact biological role remains unclear. The gene is predicted to encode a conserved protein with potential structural domains, possibly containing transmembrane regions or binding sites indicative of membrane-associated or regulatory functions.
Recombinant production of LOC644936 protein (likely via bacterial or mammalian expression systems) enables researchers to study its biochemical properties, post-translational modifications, and interactions with other biomolecules. Interest in this protein stems from its potential relevance in disease pathways, as some genomic studies link its dysregulation to cancer progression or neurological disorders. However, robust evidence connecting LOC644936 to specific pathologies is still lacking. Current applications focus on generating antibodies for localization studies, developing assay tools to map its interactome, and exploring its role in cellular models. Further characterization of recombinant LOC644936 is required to validate its physiological significance and therapeutic potential.
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