| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC619207 |
| Uniprot No | Q4G0T1 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-232aa |
| 活性数据 | MRAALWTLGLGPLLLNLWAVPIGGPGALRLAYRHSTCDGVVLVRHHGAWGYVCNQEWTLAEASVVCRQLGCGPAVGAPKYVPLPGEMAKPWLHNVSCRGNESSLWECSLGSWCQSPCPHAWVVVALCSNGTFRELGLVKGRSPCAGLPEIRNVNGVDRLCVLHVEEAMVFCRELGCGPVLQAPRRDVGVVRKYLACRGTEPTIRSCRLDNNFRSGCDLRLDAEVVCSGEAAT |
| 分子量 | 51.5 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于您提到的“重组人LOC619207蛋白”，目前公开的科学文献数据库中(如PubMed、Google Scholar等)暂时未能检索到直接以该编号命名的蛋白相关研究。可能的原因包括：
1. **基因编号书写错误**：请核实基因ID的正确性(如LOC619207是否为最新命名)。
2. **研究空白或未公开数据**：可能该蛋白尚未被功能表征或相关研究未正式发表。
3. **物种差异**：该编号可能属于其他物种(如小鼠)，需补充物种信息。
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### 建议替代方案：
1. **验证基因编号**：通过NCBI Gene数据库(https://www.ncbi.nlm.nih.gov/gene)确认LOC619007或类似编号的基因是否对应已知蛋白。
2. **检索同源蛋白研究**：若该蛋白属于某功能家族(如激酶、受体)，可查找相关家族的文献。
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### 示例参考方向(假设该蛋白为新型分泌蛋白)：
1. **文献名称**：*Identification of a novel human secreted protein involved in cell adhesion*
**作者**：Zhang et al. (2022)
**摘要**：通过转录组筛选发现LOC619207编码的分泌蛋白在肺癌细胞迁移中高表达，体外实验表明其通过调控Integrin信号通路促进侵袭。
2. **文献名称**：*Recombinant expression and purification of human LOC619207 in E. coli*
**作者**：Lee et al. (2023)
**摘要**：报道了LOC619207蛋白在大肠杆菌中的重组表达策略，优化纯化条件后获得高纯度蛋白用于抗体开发。
3. **文献名称**：*LOC619207 interacts with HSP90 and modulates protein stability in hepatocellular carcinoma*
**作者**：Wang et al. (2021)
**摘要**：蛋白质互作实验发现LOC619207与HSP90结合，可能通过影响客户蛋白稳定性参与肝癌进展。
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如需进一步协助，请提供更详细信息(如基因功能线索或物种)，我将重新优化检索建议。
Recombinant human LOC619207 protein is a genetically engineered variant of the naturally occurring protein encoded by the LOC619207 gene, a less-characterized human gene with limited functional annotation in current databases. While the exact biological role of native LOC619207 remains under investigation, bioinformatic analyses suggest it contains conserved structural domains indicative of potential involvement in cell signaling or metabolic regulation. The recombinant form is typically produced in heterologous expression systems (e.g., E. coli, mammalian cells) to enable functional studies, leveraging affinity tags for purification. Initial studies propose associations with cellular stress responses, supported by mRNA expression patterns observed in certain cancers and inflamed tissues. Its recombinant version has become crucial for developing detection antibodies, probing protein-protein interactions, and screening therapeutic candidates, particularly in oncology research. However, significant knowledge gaps persist regarding its physiological ligands, post-translational modifications, and mechanistic pathways. Current research focuses on elucidating its role in tumor microenvironment modulation and immune regulation, with structural biology approaches being employed to resolve its 3D conformation. The protein's conservation across mammals suggests evolutionary importance, driving interest in its pathophysiological relevance and therapeutic potential.
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