| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC51233 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-229aa |
| 活性数据 | MGNILTCCINSHCGWPRGKDAPCYESDTDIYETVAAATSESTTVEPGKLDVGATEGQDLQHISNQKMPTGPPEDRLSLKFLPSSEEDNDDAKILPSPVQGSSEDNLSLVCLPRSEDDDCDDDDDDDAQILPSRVQGGCYRFDSSSCSSEDNLSLVCLPRSEDDDCDDDDDDAQILPSPVQACSEDSLFLRCSLRHKDEEEEDDDDIHITARIESDLTLESLSDEEIHPG |
| 分子量 | 51.5 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是与重组人LOC51233蛋白相关的参考文献，已整理为简化格式(文献名称、作者、摘要内容)。需说明的是，"LOC51233"可能为暂用编号，部分研究可能已更新其基因名称(如C12orf57或其他)，建议结合最新数据库确认：
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1. **"Functional characterization of recombinant human LOC51233 in inflammatory pathways"**
*Author: Li et al. (2018)*
摘要：研究在大肠杆菌中重组表达LOC51233蛋白，发现其通过调控NF-κB通路抑制炎症反应，提示潜在抗炎治疗价值。
2. **"LOC51233 interacts with mitochondrial proteins: Implications for cellular energy metabolism"**
*Author: Martinez-Garcia et al. (2020)*
摘要：利用HEK293细胞重组表达LOC51233.结合质谱分析发现其与线粒体复合物I亚基相互作用，可能参与氧化磷酸化调控。
3. **"Structural insights into the role of LOC51233 in DNA damage repair"**
*Author: Chen & Wang (2019)*
摘要：解析重组LOC51233晶体结构，揭示其通过C端结构域结合单链DNA，可能辅助DNA损伤修复机制。
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**注意**：
- 若检索困难，可能因"LOC51233"为早期编号，建议查询NCBI Gene或UniProt获取最新命名(如更新为C12orf57.可补充搜索)。
- 上述摘要为模拟示例，实际文献需通过PubMed/Google Scholar以最新关键词(如重组蛋白表达系统或功能研究)确认。
**Background of Recombinant Human LOC51233 Protein**
The recombinant human LOC51233 protein is derived from the *LOC51233* gene, a locus initially identified through genomic sequencing but whose full functional characterization remains under investigation. Currently annotated as a putative protein-coding gene, LOC51233 is believed to encode a product involved in cellular processes such as RNA binding or metabolic regulation, based on sequence homology and domain predictions. Structural analyses suggest potential motifs associated with methyltransferase activity or nucleic acid interaction, though experimental validation is limited.
Recombinant production of LOC51233 typically involves expression systems like *E. coli* or mammalian cells, enabling studies on its biochemical properties and interactions. Interest in this protein stems from its differential expression patterns observed in certain cancers and inflammatory conditions, hinting at potential roles in disease pathways. However, the lack of specific antibodies or functional assays has slowed progress. Current research focuses on elucidating its subcellular localization, post-translational modifications, and molecular partners to clarify its physiological relevance.
Despite limited knowledge, recombinant LOC51233 serves as a tool for structural studies and screening for binding molecules, offering avenues for therapeutic or diagnostic exploration. Challenges include resolving its precise biological function and reconciling discrepancies between *in silico* predictions and experimental data.
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