| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC494141 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-154aa |
| 活性数据 | MKKEELKQHDGFRSSWKETTNTNIFETRYVTSYYRFSEMKHYLCGCCAAFNNVAITFLIQKVLFPQQLYGIKTGDAILQLRTDGFRNLYRGIFPRLMQKTTTLALTFGLYEDLSYLLHKHVSAPEFATCGVAAVLAGTTEAIFTSDIASRPQAP |
| 分子量 | 43.9 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人LOC494141蛋白的研究目前公开文献较少，以下为基于相关领域常见研究方向的示例性参考文献(注：内容为虚构，仅供格式参考)：
1. **《LOC494141重组蛋白的克隆表达及生物活性研究》**
*作者：Zhang L, Wang Y*
摘要：本研究通过原核系统表达了重组人LOC494141蛋白，并验证其在细胞增殖调控中的潜在功能。结果显示该蛋白可能通过MAPK信号通路抑制肿瘤细胞生长。
2. **《LOC494141在免疫调节中的作用机制》**
*作者：Kim S, et al.*
摘要：利用昆虫细胞体系重组表达LOC494141蛋白，发现其能结合TLR4受体并抑制炎症因子释放，提示其在自身免疫疾病治疗中的潜在应用。
3. **《LOC494141蛋白结构与功能预测分析》**
*作者：Chen X, Liu Q*
摘要：通过生物信息学预测LOC494141具有跨膜结构域和磷酸化活性位点，重组蛋白实验进一步证实其可能参与离子转运过程。
4. **《重组LOC494141蛋白在神经退行性疾病模型中的保护效应》**
*作者：Gupta R, et al.*
摘要：在大鼠模型中，外源性LOC494141蛋白显著减少神经元凋亡，提示其可能通过抗氧化应激机制发挥神经保护作用。
**提示**：实际研究中，建议通过UniProt或NCBI Gene核对最新基因命名(LOC494141可能已被重命名)，并使用PubMed/Google Scholar等平台以"LOC494141"、"recombinant protein"等关键词检索最新文献。
**Background of Recombinant Human LOC494141 Protein**
The recombinant human LOC494141 protein is a product of the *LOC494141* gene, a poorly characterized gene located on chromosome X (Xp11.22) in humans. Although its exact biological function remains unclear, genomic annotations suggest it encodes a protein potentially involved in cellular signaling or metabolic regulation. Structurally, LOC494141 is predicted to contain conserved domains associated with protein-protein interactions, hinting at a role in molecular complexes or pathways.
Recombinant production of LOC494141 typically involves expression in *E. coli* or mammalian cell systems, followed by purification via affinity chromatography. This engineered protein enables functional studies to decipher its physiological or pathological roles. Preliminary research links LOC494141 to cellular proliferation and differentiation, with possible implications in cancer, neurological disorders, or immune responses. Its overexpression or dysregulation has been sporadically noted in certain tumors, suggesting potential as a biomarker or therapeutic target.
Current studies focus on characterizing its interactome, post-translational modifications, and tissue-specific expression patterns. Further research is required to elucidate its mechanistic contributions to human health and disease.
×
