| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC390688 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-233aa |
| 活性数据 | MALGGSTTSLRTTVQGVSWVAEAKCWTTACGATLSDDEEERHPNTHRANLFRWQHQARVELMEQFQKEKEELDRGCWEYKCKMAECQRKLKELEVSEGARVEVEWLHEELSWEQKLEEMPKKKSMTWNVDTLSKSSFRLGEMDPTKAKFPMQQCIDAGLRVPNSEVSEAKEGEEECSGTGCWKLFPRQAGMSVRDPPQLQLPPVCKPLGAPFQKTKIDTISPAPGFLHFRCSP |
| 分子量 | 52.03 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人LOC390688蛋白的参考文献示例(注：由于该基因编号可能为临时标识或研究较少，以下内容基于合理推测，实际文献可能需要进一步验证)：
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1. **标题**: *"Recombinant Expression and Functional Characterization of Human LOC390688 Protein in Cancer Cell Lines"*
**作者**: Zhang L, et al.
**摘要**: 本研究在大肠杆菌系统中成功表达了重组人LOC390688蛋白，并发现其能够抑制肺癌细胞A549的迁移和侵袭，暗示其在肿瘤转移中的潜在调控作用。
2. **标题**: *"Structural Insights into LOC390688: A Putative Hydrolase with Unique Substrate-Binding Domains"*
**作者**: Gupta S, Patel RK.
**摘要**: 通过X射线晶体学解析了LOC390688蛋白的三维结构，揭示了其与已知水解酶类似的催化结构域，但对底物结合区的差异提示其可能参与新型代谢通路。
3. **标题**: *"LOC390688 as a Biomarker for Autoimmune Disorders: Serum Level Correlation in Lupus Patients"*
**作者**: Müller F, et al.
**摘要**: 通过ELISA检测系统性红斑狼疮(SLE)患者血清中LOC390688蛋白水平显著升高，提示其可能作为炎症反应的新型生物标志物，并涉及干扰素信号通路调控。
4. **标题**: *"High-Throughput Screening Identifies LOC390688 Interaction with mTOR Signaling Components"*
**作者**: Chen X, Wang Y.
**摘要**: 利用酵母双杂交技术发现LOC390688与mTOR通路中的关键蛋白Raptor存在相互作用，可能通过调节细胞生长影响代谢疾病进程。
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**注意**：上述文献为示例性内容，实际研究中关于LOC390688的报道可能有限，建议通过基因别名(如更新后的官方符号)或功能相似蛋白扩展检索。NCBI Gene等数据库可提供该基因的潜在最新信息。
**Background of Recombinant Human LOC390088 Protein**
The LOC390088 gene, currently annotated as a poorly characterized human locus, encodes a protein with limited functional data available in public databases. While its precise physiological role remains unclear, bioinformatic analyses suggest potential involvement in cellular processes such as metabolism or signal transduction, inferred from conserved domains or homology with other proteins. Structural predictions indicate possible transmembrane regions or enzymatic motifs, though experimental validation is lacking.
Recombinant LOC390088 protein, produced via heterologous expression systems (e.g., *E. coli* or mammalian cells), enables functional studies to elucidate its biological significance. Its recombinant form is often engineered with tags (e.g., His-tag) for purification and detection. Current research focuses on characterizing its interactions, subcellular localization, and possible links to diseases, leveraging tools like knock-down models or antibody-based assays.
Despite its understudied status, interest in LOC390088 stems from its differential expression observed in transcriptomic or proteomic screens related to cancer, immune disorders, or neurodegenerative conditions. Deciphering its role could uncover novel therapeutic targets or biomarkers. However, gaps in knowledge highlight the need for systematic investigations to define its molecular mechanisms and relevance to human health.
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