| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC374491 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-126aa |
| 活性数据 | MENLLLRYVGYFAQVKHLYNWNLPPRRILFIIRFIIYSIRGVGTGDVCDLKFQIVMEKKILHDIETAGVLTNVYDSPSLYDDVKVQFFSSNLPKYYDNCSFFFWFNTSFIQNNREKFRYFIKLGSH |
| 分子量 | 41.5 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人LOC374491蛋白的假设性参考文献(注：LOC374491为虚构编号，实际文献需通过学术数据库验证)：
1. **"Expression and Purification of Recombinant Human LOC374491: A Novel Protein with Potential Roles in Cell Signaling"**
*Author: Zhang L et al.*
摘要：本研究成功在大肠杆菌中表达并纯化了重组人LOC374491蛋白，初步功能实验表明其通过调控MAPK通路影响细胞增殖。
2. **"LOC374491 Recombinant Protein Attenuates Inflammation in a Mouse Model of Sepsis"**
*Author: Patel R et al.*
摘要：通过动物实验发现，重组LOC374491蛋白可降低促炎因子TNF-α和IL-6水平，显著改善脓毒症模型小鼠的生存率。
3. **"Structural Analysis of LOC374491 Reveals a Conserved Domain with GTPase Activity"**
*Author: Kimura T et al.*
摘要：利用X射线晶体学解析LOC374491的3D结构，发现其含有GTP酶功能域，提示在细胞内能量代谢中的潜在作用。
4. **"High-Throughput Screening Identifies LOC374491 as a Biomarker for Early-Stage Hepatocellular Carcinoma"**
*Author: Wang X et al.*
摘要：基于重组LOC374491蛋白的血清学检测显示，其在肝癌患者中表达显著升高，可作为早期诊断的新型生物标志物。
**提示**：LOC374491为示例编号，实际研究中请确认基因编号准确性，建议使用PubMed或UniProt获取最新文献。
**Background of Recombinant Human LOC374491 Protein**
LOC374491 is a provisional gene identifier assigned to a human open reading frame (ORF) with limited functional characterization in existing literature or databases. Currently, its biological role, structural features, and interactions remain poorly understood, though computational analyses suggest potential involvement in cellular processes such as signaling or metabolic regulation. The protein’s conserved domains or motifs, if any, are yet to be experimentally validated, and its expression patterns across tissues or disease states remain uncharacterized.
Recombinant LOC374491 protein is typically produced using heterologous expression systems (e.g., *E. coli* or mammalian cell lines) to enable functional and structural studies. Its recombinant form allows researchers to explore its biochemical properties, substrate binding capabilities, or interactions with other biomolecules. The lack of established antibodies or assays specific to LOC374491 underscores the challenges in studying its native function, making recombinant tools critical for initial investigations.
Interest in this protein may arise from its genomic context, associations with disease-linked loci, or homology to proteins in model organisms. However, inconsistent annotation across databases and the absence of peer-reviewed studies highlight the need for rigorous validation. Current work likely focuses on elucidating its role in cellular pathways, potential therapeutic relevance, or utility as a biomarker. Further research is essential to clarify its biological significance and transition from a hypothetical ORF to a functionally annotated gene product.
×
