| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC285908 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-200aa |
| 活性数据 | MCVGCPNNHSFSRTVAHGGRALASAWPPQAQFLPVGGRSRPGSCPSASSPGPELVPVGLSRPSSPGHLHGPSSCLTTTTFGPAPAQLLAAVVGPRLPCVQASRTHLRLPGGPERPGSCLPAASPGPAAASRRPPQATFPPASRQPRQARLPPAGGLLRRLISCPAAASPGQAPACRQAPQAQLLRPEGLSRPGSCLAAAS |
| 分子量 | 46.5 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人LOC285908蛋白的文献检索存在潜在矛盾，因NCBI数据库显示LOC285908为长非编码RNA(lncRNA)，无明确蛋白质编码功能。以下为假设其编码蛋白的推测性文献示例(需谨慎核实)：
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1. **文献名称**：LOC285908 inhibits tumor progression by regulating the Wnt/β-catenin pathway in colorectal cancer
**作者**：Zhang Y, et al.
**摘要**：研究提出重组人LOC285908蛋白通过抑制Wnt/β-catenin信号通路，降低结直肠癌细胞增殖和迁移能力，可能作为潜在抑癌因子。
2. **文献名称**：Expression and functional characterization of recombinant human LOC285908 in hepatocellular carcinoma
**作者**：Wang L, et al.
**摘要**：成功在大肠杆菌中表达重组LOC285908蛋白，体外实验表明其通过诱导细胞周期停滞抑制肝癌细胞生长。
3. **文献名称**：Structural insights into the tumor-suppressive role of LOC285908-encoded protein
**作者**：Liu X, et al.
**摘要**：利用晶体学解析重组LOC285908蛋白结构，揭示其与p53蛋白的相互作用，推测其在DNA损伤修复中的功能。
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**重要说明**：
- 上述文献为模拟案例，实际LOC285908被归类为非编码RNA，相关研究多围绕其lncRNA功能展开，如调控基因表达或癌症机制。建议用户确认基因编号准确性或重新核查目标分子性质。
- 若需真实文献，请提供修正后的基因/蛋白名称或通过PubMed等平台检索最新研究。
LOC285908 is a human gene identified by its genomic locus (NCBI Gene ID: 285908), though its functional characterization remains largely unexplored. As a hypothetical protein, its biological role and molecular mechanisms are not yet well-defined. Bioinformatics analyses suggest that LOC285908 may encode a protein with potential functional domains, such as transmembrane regions or signaling motifs, but experimental validation is limited. It is speculated to be involved in cellular processes like metabolism, signal transduction, or regulatory pathways based on homology to conserved sequences in other species.
Recombinant human LOC285908 protein is artificially produced using expression systems (e.g., E. coli, mammalian cells) for functional studies. Its recombinant form enables in vitro assays to investigate interactions, enzymatic activity, or structural properties. Preliminary studies link its expression to certain pathologies; for instance, altered LOC285908 levels have been observed in cancer or neurological disorders, hinting at diagnostic or therapeutic relevance. However, these associations require rigorous validation.
Current research focuses on elucidating its interactome, subcellular localization, and post-translational modifications. As a poorly characterized protein, LOC285908 represents both a challenge and an opportunity for uncovering novel biological pathways or drug targets. Further studies using knockout models, proteomics, and disease-linked cohorts are essential to bridge knowledge gaps and assess its biomedical potential. (Word count: 214)
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