| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC284067 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-164aa |
| 活性数据 | MNNSLDYLAYPVIVSNHRQSTTFRKKLDFGHYVSHKNRIQIAKPTVDTKPPVAHTNHILKLSKLQGEQKKINKIEYENKQLCQKIANAHRGPAKVDCWNEYFSKSLNRETRNRELVRITMENQGILKRLVDRKPHYDRRASEIDWQNSRRYIRNTTRYLLSQNE |
| 分子量 | 45.9 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人LOC284067蛋白的假设性参考文献示例。由于LOC284067可能是暂定基因符号，且相关研究较少，实际文献可能有限。建议通过NCBI、PubMed或UniProt等数据库获取最新信息。
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1. **文献名称**：*Characterization of the Novel Human Protein LOC284067: Expression Patterns and Structural Insights*
**作者**：Zhang L, et al.
**摘要**：本研究首次报道了LOC284067的分子克隆及重组蛋白表达。通过生物信息学预测其具有α-螺旋富集结构域，并在多种癌细胞系中检测到mRNA的高表达，提示其可能与肿瘤发生相关。
2. **文献名称**：*LOC284067 Interacts with p53 Pathway: A Potential Tumor Suppressor Role*
**作者**：Kimura T, et al.
**摘要**：通过免疫共沉淀实验发现，重组LOC284067蛋白与p53蛋白存在直接相互作用，可能通过调控p53下游基因参与DNA损伤修复。敲低实验显示细胞增殖加快，提示其抑癌功能。
3. **文献名称**：*LOC284067 in Neuronal Development: Evidence from CRISPR/Cas9 Knockout Models*
**作者**：Chen R, et al.
**摘要**：在小鼠模型中敲除LOC284067导致神经突生长异常，推测其通过调节微管动力学影响神经元分化。重组蛋白体外实验证实其促进海马神经元轴突延伸。
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**注意**：上述文献为假设性示例，实际研究可能不存在或该基因功能尚未明确。建议通过以下途径进一步验证：
- 查询NCBI Gene数据库(Gene ID: 284067)
- 检索PubMed相关关键词(如“LOC284067 recombinant protein”)
- 联系领域内专家或关注最新功能基因组学研究。
**Background of Recombinant Human LOC284067 Protein**
The recombinant human LOC284067 protein is derived from the LOC284067 gene, a locus currently annotated as a long non-coding RNA (lncRNA) or a putative protein-coding gene with limited functional characterization. Although its precise biological role remains unclear, LOC284067 has been preliminarily linked to cellular processes such as proliferation, differentiation, and metabolic regulation. Studies suggest potential associations with cancer progression, where aberrant expression patterns have been observed in tumor tissues, implicating it as a possible biomarker or therapeutic target.
The recombinant form is engineered using expression systems (e.g., *E. coli* or mammalian cells) to produce the protein in vitro, enabling functional studies. Structural predictions indicate conserved domains potentially involved in protein-protein interactions or enzymatic activity, though experimental validation is lacking. Research efforts focus on elucidating its interaction networks, signaling pathways (e.g., Wnt or MAPK), and roles in disease mechanisms. Challenges include resolving discrepancies in its coding potential and clarifying its molecular mechanisms. Further investigation of recombinant LOC284067 could advance understanding of its physiological relevance and translational applications in biomedicine.
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