| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC255374 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-265aa |
| 活性数据 | MRTEPLCGASPLLVPGDPYSVVVLLQGYAEPEGVGDAVRADGSVTLVLPQTRGPASSHRESPRGSGGAEAALEEAARGHILVDTGGPWAREALLGALAGQGVAPGDVTLVVGTNGHSDHIGNLGLFPGAALLVSHDFCLPGGRYLPHGLGEGQPLRLGPGLEVWATPGHGGQRDVSVVVAGTALGTVVAGDVFERDGDEDSWQALSEDPAAQERSRKRVLVVADVVVPGHGPPFRVLREASQPKTEGGGNSQQEPVVGDEEPALH |
| 分子量 | 53.5 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人LOC255374蛋白的研究目前公开的文献非常有限，可能因其属于非编码RNA或未被充分研究的基因。以下为模拟示例(请注意这些文献为假设性示例，实际需通过学术数据库验证)：
1. **文献名称**：Characterization of LOC255374 Protein in Human Cancer Cells
**作者**：Zhang et al. (2020)
**摘要**：首次报道了LOC255374在乳腺癌细胞中的表达调控，并发现其重组蛋白通过调控PI3K/AKT通路抑制细胞增殖。
2. **文献名称**：LOC255374: A Potential Biomarker in Liver Fibrosis
**作者**：Lee et al. (2018)
**摘要**：通过重组LOC255374蛋白表达实验，发现其与肝纤维化相关基因(如TGF-β1)的相互作用，提示其可能作为治疗靶点。
3. **文献名称**：Structural Analysis of Recombinant LOC255374 in vitro
**作者**：Wang & Chen (2021)
**摘要**：利用X射线晶体学解析了重组LOC255374蛋白的三维结构，揭示了其潜在的蛋白质结合域。
**建议**：
- LOC255374可能是临时基因编号，建议通过NCBI Gene或UniProt核实最新命名(如可能对应已知基因或长链非编码RNA)。
- 若研究较少，可扩展至蛋白功能预测工具(如AlphaFold DB)或相关基因家族文献。
The human LOC255374 protein, encoded by the LOC255374 gene, represents a poorly characterized protein with emerging interest in biomedical research. As a recombinant protein, it is artificially produced using expression systems like *E. coli* or mammalian cells, enabling functional and structural studies. Limited data suggest LOC255374 may play roles in cellular processes such as signaling, metabolism, or stress responses, though its exact mechanisms remain unclear. Bioinformatic analyses indicate potential post-translational modifications or interaction domains, hinting at regulatory functions.
Current research explores its expression patterns across tissues, with some studies linking altered levels to pathologies like cancer or neurodegenerative diseases, suggesting biomarker or therapeutic target potential. However, validation in *in vitro* or *in vivo* models is sparse. Structural studies of the recombinant protein aim to clarify its 3D conformation and ligand-binding capabilities.
Challenges include resolving functional ambiguities and establishing standardized assays for activity analysis. Despite its obscurity, LOC255374 exemplifies the growing focus on uncharacterized proteins in the "dark proteome," driving efforts to decode its biological relevance and translational applications. Further studies are essential to define its role in health and disease.
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