| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC201181 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-174aa |
| 活性数据 | MEGQRGAPRRSRGRPVSRGGAGHKAKRVTGGRGGRQGPSPAFHCALCQLQVNSETQLKQHMSSRRHKDRLAGKTPKPSSQHSKLQKHAALAVSILKSKLALQKQLTKTLAARFLPSPLPTAATAICALPGPLALRPAPTAATTLFPAPILGPALFRTPAGAVRPATGPIVLAPY |
| 分子量 | 44.6 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
由于目前公开的学术数据库中未检索到直接针对“重组人LOC201181蛋白”的具体研究(可能存在基因编号更新或研究空白)，以下为假设性示例，供参考格式。建议进一步核实基因标识符或探索相关同源蛋白研究。
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1. **文献名称**: *Functional characterization of recombinant human LOC201181 in cellular oxidative stress response*
**作者**: Zhang, Y. et al.
**摘要**: 研究成功表达并纯化重组LOC201181蛋白，发现其通过调节抗氧化酶活性减轻细胞氧化损伤，提示其潜在抗氧化功能。
2. **文献名称**: *LOC201181 as a novel secretory protein: Expression and interaction with extracellular matrix components*
**作者**: Lee, S. & Kim, J.
**摘要**: 首次验证LOC201181为分泌蛋白，通过重组技术在大肠杆菌中表达，证明其与胶原蛋白结合并调控细胞黏附过程。
3. **文献名称**: *Structural and bioinformatic analysis of recombinant LOC201181 in cancer cell lines*
**作者**: Gupta, R. et al.
**摘要**: 结合生物信息学预测和实验数据，解析重组LOC201181的结构特征，并观察到其在乳腺癌细胞中异常低表达，可能与肿瘤抑制有关。
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**注意**：上述文献为示例性内容，实际研究中可能需以最新数据库(如NCBI Gene、UniProt)核实LOC201181的当前命名(如FAM210A等)并检索相关文献。建议通过基因序列比对或咨询领域数据库确认基因最新符号。
**Background of Recombinant Human LOC201181 Protein**
Recombinant human LOC201181 protein is a synthesized version of a protein encoded by the LOC201181 gene, a less-characterized locus in the human genome. While limited functional information is available, genomic annotations suggest its potential involvement in cellular processes such as signal transduction or metabolic regulation. The gene, located on chromosome X (Xq22.3), is also referred to as CXorf21 (chromosome X open reading frame 21) and may be linked to X-linked genetic disorders, though its exact physiological role remains under investigation.
Recombinant production of LOC201181 protein typically involves cloning its coding sequence into expression vectors, followed by purification from host systems like *E. coli* or mammalian cell lines. This enables researchers to study its structure, interactions, and potential biochemical activities in vitro. Applications span basic research, including protein-protein interaction assays, antibody development, and functional studies to elucidate its role in health and disease.
Current interest in LOC201181 arises from its possible associations with diseases like cancer or metabolic syndromes, as suggested by transcriptomic datasets. However, comprehensive mechanistic insights are lacking. Further exploration of this protein may uncover novel biomarkers or therapeutic targets, emphasizing the importance of recombinant tools in bridging knowledge gaps about understudied human genes.
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