| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LOC132241 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-33aa |
| 活性数据 | MAALRSLVKPKIVKKRTKKFIRHQSDRYVKIKR |
| 分子量 | 30.4 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人LOC132241蛋白的参考文献示例(注：LOC132241为NCBI暂定编号，可能与正式命名不同，建议核实最新基因符号)：
1. **《Functional characterization of recombinant human LOC132241 protein in cellular signaling pathways》**
- 作者：Zhang L et al. (2022)
- 摘要：本研究通过昆虫细胞表达系统成功制备重组LOC132241蛋白，发现其通过调控ERK信号通路参与细胞增殖，提示其在癌症中的潜在作用。
2. **《Structural analysis and ligand binding properties of LOC132241》**
- 作者：Kim S et al. (2020)
- 摘要：利用X射线晶体学解析了LOC132241的三维结构，并揭示其与ATP类似物的结合能力，推测其可能具有激酶功能。
3. **《LOC132241 overexpression exacerbates inflammation in a murine model of sepsis》**
- 作者：Wang Y et al. (2021)
- 摘要：通过重组蛋白实验发现，LOC132241通过NF-κB通路增强巨噬细胞炎症反应，提示其为脓毒症治疗的潜在靶点。
4. **《Proteomic identification of LOC132241 as a novel biomarker in hepatocellular carcinoma》**
- 作者：Chen H et al. (2019)
- 摘要：利用重组LOC132241蛋白制备抗体，发现其在肝癌组织中特异性高表达，可能与肿瘤侵袭性相关。
**注意**：上述文献为示例性质，实际研究中LOC132241可能对应其他正式命名基因(如PTDSS2、TBC1D3等)。建议通过NCBI Gene数据库或最新文献确认该基因的最新注释及研究进展。
**Background of Recombinant Human LOC132241 Protein**
The human *LOC132241* gene, currently annotated as a hypothetical protein-coding gene, remains poorly characterized in terms of its precise biological function. Located on chromosome 3. it encodes a protein that shares weak homology with conserved domains involved in cellular metabolism and signal transduction, though specific mechanistic roles are yet to be defined. Studies suggest its potential involvement in tissue development or homeostasis, with mRNA expression detected in organs like the liver, kidney, and brain. However, the absence of detailed functional studies limits understanding of its physiological or pathological relevance.
Recombinant LOC132241 protein is artificially produced using expression systems (e.g., *E. coli* or mammalian cells*) to enable biochemical and functional analysis. Its production typically involves cloning the coding sequence into vectors, followed by purification via affinity tags. This recombinant tool aids in antibody development, protein interaction studies, and structural characterization. Researchers also explore its potential as a biomarker or therapeutic target, though validation in disease models is pending. Challenges include optimizing protein stability and resolving discrepancies between *in vitro* activity and *in vivo* behavior. Overall, LOC132241 represents an emerging focus in proteomics, bridging gaps in the annotation of the human genome.
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