| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | LBX2 |
| Uniprot No | Q6XYB7 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-194aa |
| 活性数据 | MGKRTSLEVSLGELGGEKCRGGRRSFPPLAASRPARPGGWRWARRDLCKTASRAENNSQACRPQRRAGPDALGPGPFGRKRRKSRTAFTAQQVLELERRFVFQKYLAPSERDGLATRLGLANAQVVTWFQNRRAKLKRDVEEMRADVASLRALSPEVLCSLALPEGAPDPGLCLGPAGPDSRPHLSDEEIQVDD |
| 分子量 | 47.8 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人LBX2蛋白的模拟参考文献示例(注：以下内容为虚构，仅用于示例格式)：
1. **文献名称**: "LBX2 promotes skeletal muscle regeneration through regulation of satellite cell differentiation"
**作者**: Yamamoto A, et al.
**摘要**: 研究揭示了重组人LBX2蛋白在小鼠骨骼肌损伤模型中促进卫星细胞分化和肌肉再生的机制，表明LBX2通过调控MyoD和Myogenin表达发挥作用。
2. **文献名称**: "Recombinant human LBX2 protein inhibits tumor growth by suppressing Wnt/β-catenin signaling in colorectal cancer"
**作者**: Chen L, et al.
**摘要**: 通过体外和体内实验证明，重组人LBX2蛋白可靶向Wnt通路，抑制结直肠癌细胞增殖并诱导凋亡，为癌症治疗提供潜在策略。
3. **文献名称**: "Expression and purification of bioactive recombinant human LBX2 in E. coli for functional studies"
**作者**: Smith J, et al.
**摘要**: 报道了一种通过大肠杆菌系统高效表达重组人LBX2蛋白的方法，经亲和层析纯化后验证其与DNA结合活性，为后续功能研究奠定基础。
4. **文献名称**: "LBX2 modulates cardiac development by interacting with TBX5 in zebrafish models"
**作者**: Wang H, et al.
**摘要**: 利用斑马鱼模型发现重组人LBX2蛋白通过结合TBX5转录因子调控心脏形态发生，突变导致心室发育异常，提示其在先天性心脏病中的作用。
建议通过PubMed、Web of Science或Google Scholar检索实际文献，关键词：**recombinant human LBX2 protein**, **LBX2 function**, **gene regulation**等。
Lbx2 (Ladybird homeobox 2) is a member of the homeobox transcription factor family, characterized by a conserved DNA-binding homeodomain. It plays crucial roles in embryonic development, particularly in organogenesis and tissue patterning. Studies suggest its involvement in the development of the nervous system, heart, and skeletal muscle. In humans, LBX2 has been linked to congenital disorders and cancer progression, with emerging evidence indicating its regulatory functions in cell migration, proliferation, and differentiation. The recombinant human LBX2 protein is engineered for in vitro studies to decipher its molecular mechanisms. Produced via expression systems like E. coli or mammalian cells, it retains DNA-binding activity and functional interactions with co-regulators. Researchers utilize this purified protein for structural analysis, chromatin immunoprecipitation, and pathway mapping to explore its role in developmental biology or disease pathogenesis. Its applications extend to screening therapeutic agents targeting LBX2-associated conditions. Quality-controlled batches ensure consistency in biochemical assays and cell-based experiments. Current research focuses on its interplay with signaling pathways (e.g., Wnt, TGF-β) and epigenetic modifiers, aiming to unravel its tissue-specific regulatory networks and clinical potential.
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