| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | KIAA0892 |
| Uniprot No | Q9Y6X3 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-613aa |
| 活性数据 | MAAQAAAAAQ AAAAQAAQAE AADSWYLALL GFAEHFRTSS PPKIRLCVHC LQAVFPFKPP QRIEARTHLQ LGSVLYHHTK NSEQARSHLE KAWLISQQIP QFEDVKFEAA SLLSELYCQE NSVDAAKPLL RKAIQISQQT PYWHCRLLFQ LAQLHTLEKD LVSACDLLGV GAEYARVVGS EYTRALFLLS KGMLLLMERK LQEVHPLLTL CGQIVENWQG NPIQKESLRV FFLVLQVTHY LDAGQVKSVK PCLKQLQQCI QTISTLHDDE ILPSNPADLF HWLPKEHMCV LVYLVTVMHS MQAGYLEKAQ KYTDKALMQL EKLKMLDCSP ILSSFQVILL EHIIMCRLVT GHKATALQEI SQVCQLCQQS PRLFSNHAAQ LHTLLGLYCV SVNCMDNAEA QFTTALRLTN HQELWAFIVT NLASVYIREG NRHQEVLYSL LERINPDHSF PVSSHCLRAA AFYVRGLFSF FQGRYNEAKR FLRETLKMSN AEDLNRLTAC SLVLLGHIFY VLGNHRESNN MVVPAMQLAS KIPDMSVQLW SSALLRDLNK ACGNAMDAHE AAQMHQNFSQ QLLQDHIEAC SLPEHNLITW TDGPPPVQFQ AQNGPNTSLA SLL |
| 分子量 | 69 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下为虚构的参考文献示例，供参考格式。实际文献需通过学术数据库检索：
1. **文献名称**：*"Expression and Functional Characterization of Recombinant Human KIAA0892 in Cell Cycle Regulation"*
**作者**：Zhang L, et al.
**摘要**：本研究成功在大肠杆菌中表达并纯化了重组人KIAA0892蛋白，发现其通过结合细胞周期蛋白依赖性激酶(CDK)调控G1/S期转换，提示其在细胞增殖中起关键作用。
2. **文献名称**：*"KIAA0892 Interacts with Autophagy-Related Proteins: Insights from Structural Analysis"*
**作者**：Tanaka M, et al.
**摘要**：通过体外实验证实重组人KIAA0892蛋白与LC3和p62存在相互作用，其C端结构域对自噬体形成至关重要，可能参与神经退行性疾病通路。
3. **文献名称**：*"Proteomic Identification of KIAA0892 as a Novel Tumor Suppressor in Gastric Cancer"*
**作者**：Chen X, et al.
**摘要**：重组KIAA0892蛋白的过表达抑制胃癌细胞迁移和侵袭，机制涉及Wnt/β-catenin信号通路下调，提示其作为潜在治疗靶点。
**提示**：实际研究中建议通过PubMed、Web of Science或Google Scholar检索真实文献，可使用关键词“recombinant KIAA0892”或“KIAA0892 protein function”。
Recombinant human KIAA0892 protein, derived from the KIAA0892 gene, is a subject of emerging interest in molecular and cellular biology. Initially identified through large-scale sequencing projects, the KIAA0892 gene encodes a protein of unknown precise function, though its structural domains suggest involvement in intracellular signaling or structural organization. Bioinformatic analyses predict KIAA0892 contains coiled-coil regions and phosphorylation sites, hinting at roles in protein-protein interactions or regulatory pathways.
Studies link KIAA0892 to cellular processes like membrane trafficking, cytoskeletal dynamics, and possibly autophagy. Its expression profile varies across tissues, with higher levels observed in brain, liver, and kidney, implying tissue-specific functions. Dysregulation of KIAA0892 has been tentatively associated with neurological disorders, cancer progression, and metabolic syndromes, though mechanistic insights remain limited.
Recombinant KIAA0892 protein is typically produced via heterologous expression systems (e.g., E. coli, mammalian cells) for functional studies. It enables biochemical characterization, antibody development, and exploration of its interactome. Researchers utilize it to clarify its role in disease pathogenesis and potential as a therapeutic target. Current challenges include resolving its 3D structure and delineating signaling cross-talk. As tools advance, KIAA0892 may emerge as a key player in cellular homeostasis and disease mechanisms.
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