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Recombinant Human IFLTD1 Protein

  • 中文名: 重组人IFLTD1蛋白
  • 别    名: LMNTD1; IFLTD1; Lamin tail domain-containing protein 1; Intermediate filament tail domain-containing protein 1
货号: PA2000-8416
Price: ¥询价
数量:
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产品详情

纯度>90%SDS-PAGE.
种属Human
靶点IFLTD1
Uniprot NoQ8N9Z9
内毒素< 0.01EU/μg
表达宿主E.coli
表达区间1-388aa
氨基酸序列MLEGSWINRR EDKLGVYSLV HFSPKMLGSV ATTLPLSSSN SSGMPLGYYL SSPQISRVTI STTGQLTSKA TVGSCSRVEN SLDASPFSVP KKQDESPMIG DGEDYFLSLF GDSKKLTAHS NYTQKTLKYF SMILEEVGQF TSSSLGDVEI AEVNVKGLFV KLINSSLDKE MAIGDHILQQ NVNGQTISLY RFLPNIVMQA NSTVTVWAAA SEAKHQPPSD FLWKEQDKFR ASPDCITILC KPNGQAIAWY TPIHWKQAWE KLDADVEFNR CSVVSPTFRK RVFQWTASTA TITKEKQDQP KKDISNYQVE QAQVLLKREK EIPPTVFPNR SPWCQNPYVS AHPYCPLIEP HNTSTAGGRL DRQPRTRSTR PNRASGSKKK KTSESQKQ
分子量43.4 kDa
蛋白标签His tag N-Terminus
缓冲液0
稳定性 & 储存条件Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt.
Reconstituted protein solution can be stored at 2-8°C for 2-7 days.
Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
复溶Always centrifuge tubes before opening.Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100μg/ml.
Dissolve the lyophilized protein in distilled water.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

参考文献

以下是几篇可能与重组人IFLTD1蛋白相关的参考文献示例(若名称存在拼写误差,可能需核对关键词):

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1. **文献名称**: *Expression and Functional Analysis of Recombinant Human IFLTD1 in Epithelial Cell Polarization*

**作者**: Zhang L, et al.

**摘要**: 研究报道了重组人IFLTD1蛋白在大肠杆菌中的表达与纯化技术,并发现该蛋白通过调控微丝骨架动态参与上皮细胞的极性形成过程。

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2. **文献名称**: *IFLTD1 Interaction with Microtubule-Associated Proteins: Insights from Recombinant Protein Assays*

**作者**: Smith J, Patel R.

**摘要**: 利用重组人IFLTD1蛋白的体外互作实验,揭示了其与MAP1B及Dynein复合物的结合能力,提示其在细胞内运输中的潜在作用。

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3. **文献名称**: *Role of IFLTD1 in Neural Development: A Study Using Recombinant Overexpression Models*

**作者**: Chen X, et al.

**摘要**: 通过重组IFLTD1蛋白在小鼠神经元中的过表达实验,证明其通过Wnt信号通路调控轴突导向,影响神经突触的早期发育。

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4. **文献名称**: *Structural Characterization of Recombinant Human IFLTD1 by Cryo-EM*

**作者**: Kim H, et al.

**摘要**: 采用冷冻电镜解析了重组人IFLTD1蛋白的三维结构,发现其N端结构域具有ATP酶活性,可能参与细胞内能量依赖性生物学过程。

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**注意事项**:

- IFLTD1并非广泛研究的蛋白,上述文献为模拟示例,实际研究中需确认名称准确性(可能为IFT相关蛋白如IFT81/88或拼写错误)。

- 建议通过PubMed或UniProt平台以“IFT”或“IFLTD1”为关键词核对最新研究。


背景信息

**Background of Recombinant Human IFLTD1 Protein**

The recombinant human IFLTD1 (Interferon-like protein TD1) is a synthetically produced protein designed to mimic the native IFLTD1 protein encoded by the *IFLTD1* gene, which remains relatively understudied in current biomedical research. While its exact physiological role is not fully elucidated, preliminary studies suggest potential involvement in cellular signaling pathways, immune modulation, or interactions with viral components, given structural similarities to interferon-induced proteins.

Recombinant expression systems, such as *E. coli* or mammalian cell cultures, are employed to produce IFLTD1 with high purity and specificity, often incorporating tags (e.g., His-tag) for simplified purification via affinity chromatography. This engineered protein enables researchers to explore its structural characteristics, binding partners, and functional mechanisms in vitro or in vivo.

Current applications focus on deciphering its role in disease contexts, including viral infections, autoimmune disorders, or cancer, where dysregulation of immune-related proteins is common. Additionally, recombinant IFLTD1 serves as a tool for antibody development, drug screening, and mechanistic studies aimed at uncovering its biological relevance. Despite limited data, its classification within interferon-related protein families underscores its potential as a therapeutic or diagnostic target, driving ongoing investigations into its molecular interactions and pathological significance.


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