关键信息
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基因名
CALCB
- 应用
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别名
CALCB；CALC2；Calcitonin gene-related peptide 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P10092
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表达区间
1-118aa
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氨基酸序列
MGFRKFSPFL ALSILVLYQA GSLQAAPFRS ALESSPDPAT LSKEDARLLL AALVQDYVQM KASELKQEQE TQGSSSAAQK RACNTATCVT HRLAGLLSRS GGMVKSNFVP TNVGSKAF
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分子量
36 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CALCB (Calcitonin Gene-Related Peptide Beta) is a neuropeptide that plays significant roles in various physiological processes, including pain modulation, cardiovascular regulation, and neurogenic inflammation. Its abundant presence in the central and peripheral nervous systems has piqued interest among researchers investigating its potential therapeutic applications, particularly in pain management and neurodegenerative diseases. The complexity of CALCB's biological functions necessitates advanced study into its structure and activity. Recombinant protein production of CALCB allows for detailed characterization of its properties and interactions with receptors and other biomolecules. This research not only enhances our understanding of CALCB's role in signaling pathways but also aids in the development of novel treatments targeting conditions linked to CALCB dysregulation, such as chronic pain syndromes and migraine. Furthermore, the recombinant CALCB can be utilized in drug discovery processes, providing a platform for high-throughput screening of potential pharmacological agents. Overall, the investigation into CALCB recombinant proteins is crucial for unlocking new therapeutic strategies and improving outcomes for patients suffering from various neurological disorders.
