Recombinant Human PGRMC1 Protein，GST

PGRMC1 (Progesterone Receptor Membrane Component 1) is a 25 kDa protein that plays a crucial role in various physiological processes, including cell survival, proliferation, and differentiation. Initially identified as a receptor for progesterone, PGRMC1 has since been implicated in non-genomic signaling pathways that influence cell behavior in response to hormones and other stimuli. Its involvement in cancer biology has garnered significant attention, as elevated levels of PGRMC1 are often associated with poor prognosis in various malignancies, including breast and ovarian cancers. Recent studies have also highlighted PGRMC1's role in modulating the effects of other steroid hormones and its interaction with key signaling molecules. Consequently, recombinant PGRMC1 protein has become a valuable tool for researchers seeking to elucidate its functional mechanisms and explore its potential as a therapeutic target. Understanding the structure and dynamics of PGRMC1 through recombinant protein studies can provide insights into its interaction networks, leading to the identification of novel strategies for cancer treatment and the development of targeted therapies. As research continues to uncover the multifaceted roles of PGRMC1 in human health and disease, the recombinant protein serves as a foundation for advancing our knowledge and developing interventions that may mitigate the effects of steroid hormone dysregulation.