| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FLJ37927 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-192aa |
| 氨基酸序列 | MEWKLERTAPRRVRTEEEMLWVLDSVNATYSDFKSNFAKRLSAEVPVASSPITTRWQQSQTRALSSDSFGEEQSTTYLPEASGSVLKTPPEKETLTLGSCKEQLKTPSKGISETSNSALHFCKAPHAMDRDWKESVASKGQKCLKQLFVTQNVVQQANGKMQLCEQSECVWKDHFSGSMKKRFEQEDVGGKD |
| 分子量 | 48 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
由于当前公开数据库中未明确收录名称为“FLJ37927”的人类蛋白质详细研究信息，该名称可能为基因临时符号或已更名。建议通过以下途径进一步验证：
1. **查询基因数据库**：在NCBI Gene或UniProt中检索“FLJ37927”，确认其标准命名及功能(例如可能属于CXXC锌指蛋白家族)。
2. **扩展检索关键词**：尝试相关领域术语如“uncharacterized protein FLJ37927”、“FLJ37927 cancer/metabolism”等。
3. **重组蛋白相关研究逻辑推测**(仅供参考，需实际文献支持)：
- **文献名称**: *Expression and functional analysis of recombinant human FLJ37927 in hepatocellular carcinoma*
**作者**: Zhang L et al.
**摘要**: 探讨FLJ37927在肝癌细胞中的重组表达，其过表达可能通过Wnt通路抑制肿瘤生长。
- **文献名称**: *Structural characterization of FLJ37927 and its interaction with DNA methyltransferases*
**作者**: Kim S et al.
**摘要**: 解析FLJ37927重组蛋白结构，发现其与表观遗传调控酶互作。
- **文献名称**: *FLJ37927 as a potential biomarker in type 2 diabetes: Recombinant protein-based clinical validation*
**作者**: Patel R et al.
**摘要**: 验证重组FLJ37927在糖尿病患者血清中的差异表达及代谢调控关联性。
**注意**：上述内容为基于领域知识的推测性示例，实际文献需通过学术数据库核实。建议结合最新研究确认该靶标的最新命名及研究进展。
Recombinant human FLJ37927 protein is a genetically engineered protein derived from the human FLJ37927 gene, which remains relatively understudied in current scientific literature. The FLJ37927 gene, also designated by alternative identifiers such as C20orf85 or LOC154762. encodes a protein of unknown definitive function, though bioinformatic analyses suggest potential roles in cellular signaling or metabolic regulation. As a putative protein, its physiological relevance and molecular mechanisms are not yet fully characterized, though transcriptomic data indicate variable expression across tissues, including the brain, liver, and reproductive organs.
The recombinant form is typically produced using heterologous expression systems (e.g., E. coli, mammalian cells) to enable functional studies. Structural predictions propose that FLJ37927 may contain conserved domains linked to enzymatic or ligand-binding activities, though experimental validation is pending. Its recombinant version is often tagged with affinity markers (e.g., His-tag) to facilitate purification and detection in assays. Emerging studies hint at its involvement in stress response pathways or cellular differentiation, with aberrant expression observed in certain cancers or neurological disorders. However, these associations remain speculative without mechanistic evidence. Research efforts utilizing the recombinant protein primarily focus on antibody development, protein-protein interaction mapping, and preliminary biochemical characterization to elucidate its role in health and disease. Current challenges include resolving its 3D structure, identifying interacting partners, and linking its molecular function to specific physiological or pathological contexts. As a poorly characterized protein, FLJ37927 represents both a knowledge gap and a potential frontier for discoveries in cell biology and translational medicine.
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