| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FLJ22662 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-223aa |
| 氨基酸序列 | MMADSGKRWADIFSKYNSGTYNNQYMVLDLKKVKLNHSLDKGTLYIVEQIPTYVEYSEQTDVLRKGYWPSYNVPFHEKIYNWSGYPLLVQKLGLDYSYDLAPRAKIFRRDQGKVTDTASMKYIMRYNNYKKDPYSRGDPCNTICCREDLNSPNPSPGGCYDTKVADIYLASQYTSYAISGPTVQGGLPVFRWDRFNKTLHQGMAEVYNFDFITMKPILKLDIK |
| 分子量 | 50.27 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是基于假设性研究的参考文献示例(请注意，这些文献为虚构示例，用于演示格式，实际研究中请通过学术数据库核实真实文献)：
1. **文献名称**: "Cloning and characterization of recombinant human FLJ22662 protein in E. coli expression system"
**作者**: Zhang, L. et al.
**摘要**: 本文报道了通过大肠杆菌表达系统成功克隆并纯化重组人FLJ22662蛋白的方法，验证了其分子量为35 kDa，并通过质谱和Western blot确认了蛋白特异性。
2. **文献名称**: "FLJ22662 interacts with mTOR signaling pathway to regulate cell proliferation"
**作者**: Tanaka, K. et al.
**摘要**: 研究发现重组人FLJ22662蛋白通过结合mTOR复合物1(mTORC1)抑制肿瘤细胞增殖，提示其可能作为癌症治疗的潜在靶点。
3. **文献名称**: "Structural insights into FLJ22662's role in metabolic regulation"
**作者**: Smith, J.R. et al.
**摘要**: 通过X射线晶体学解析了FLJ22662蛋白的三维结构，揭示了其与脂肪酸代谢酶的相互作用位点，可能参与能量稳态调控。
4. **文献名称**: "FLJ22662 knockout mice exhibit impaired mitochondrial function"
**作者**: Chen, X. & Wang, H.
**摘要**: 研究利用基因敲除模型发现，FLJ22662缺失导致小鼠线体功能异常及肌肉萎缩，支持该蛋白在维持线粒体健康中的关键作用。
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如需查找真实文献，建议通过 **PubMed** 或 **Google Scholar** 检索关键词：
`"FLJ22662" OR "C14orf105" (已知别名) + "recombinant"`，可能涉及功能、结构或疾病关联研究。
**Background of Recombinant Human FLJ22662 Protein**
The recombinant human FLJ22662 protein is a product of the *FLJ22662* gene, a poorly characterized gene identified through genomic sequencing efforts. Its biological function remains largely unexplored, though bioinformatic analyses suggest potential roles in cellular processes such as signal transduction, metabolic regulation, or nucleic acid binding due to predicted structural motifs.
FLJ22662 is expressed in various tissues, including the brain, liver, and immune cells, indicating possible tissue-specific functions. Recombinant production of FLJ22662 typically involves cloning the cDNA into expression systems (e.g., *E. coli* or mammalian cells) to produce purified, tagged proteins for functional studies. Its recombinant form enables researchers to investigate interactions, enzymatic activities, or cellular localization in vitro or in vivo.
Current research focuses on elucidating its role in disease contexts, such as cancer or neurodegenerative disorders, where differential expression patterns have been observed. Challenges include the lack of specific antibodies, undefined interactome, and limited functional data. Further studies are needed to validate hypotheses derived from computational predictions and clarify its physiological significance. This protein represents an emerging target for understanding novel molecular pathways in human health and disease.
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