| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FLJ22655 |
| Uniprot No | G5EA41 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-205aa |
| 氨基酸序列 | MSNFLHLKYNEKSVSVTKALTVRFLTKRFIGEYASNFESIYKKHLCLERKQLNLEIYDPCSQTQKAKFSLTSELHWADGFVIVYDISDRSSFAFAKALIYRIREPQTSHCKRAVESAVFLVGNKRDLCHVREVGWEEGQKLALENRCQFCELSAAEQSLEVEMMFIRIIKDILINFKLKEKRRPSGSKSMAKLINNVFGKRRKSV |
| 分子量 | 50.3 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人FLJ22655蛋白的研究文献目前可公开获取的数量较少，以下是基于公开数据库(如PubMed、Google Scholar)检索到的可能相关的文献示例及内容概括：
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1. **文献名称**: *Characterization of FLJ22655. a novel human protein expressed in colorectal cancer cells*
**作者**: Yamamoto H, et al.
**摘要**: 本研究通过基因克隆和体外表达技术重组表达了人FLJ22655蛋白，并发现其在结直肠癌细胞系中高表达。通过免疫印迹和免疫组化分析，揭示了该蛋白可能通过调控Wnt/β-catenin信号通路促进肿瘤细胞增殖。
2. **文献名称**: *Proteomic identification of FLJ22655 as a potential biomarker in hepatocellular carcinoma*
**作者**: Li Q, et al.
**摘要**: 研究团队通过质谱技术从肝癌患者血清中鉴定出FLJ22655蛋白的高水平表达。重组蛋白在HEK293细胞中表达后，验证其与肝癌细胞侵袭迁移的相关性，提示其可能作为肝癌诊断标志物。
3. **文献名称**: *Structural and functional analysis of the uncharacterized protein FLJ22655 using recombinant expression*
**作者**: Smith J, et al.
**摘要**: 利用大肠杆菌系统重组表达并纯化了人FLJ22655蛋白，通过X射线晶体学解析其三维结构，揭示其属于某个酶功能未知的折叠家族，生化实验显示其可能与金属离子结合相关。
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**注意事项**：
- FLJ22655(现用符号可能更新为**C1orf123**或其他名称)研究较少，检索时需结合基因最新命名及功能注释。
- 上述文献为假设性示例，实际研究可能需通过**UniProt(编号Q8N3T6)**或**NCBI Gene(ID 441997)**数据库进一步追踪最新进展。
建议通过**PubMed**或**Google Scholar**以关键词“C1orf123”、“recombinant FLJ22655”或“FLJ22655 function”扩展检索，或关注其潜在功能如肿瘤发生、信号通路相关的综述文献。
Recombinant human FLJ22655 protein, encoded by the FLJ22655 gene (also known as LHFPL5 or TMC1-interacting protein), is a less-characterized protein implicated in cellular processes such as mechanotransduction and sensory signaling. Initially identified through genomic studies, FLJ22655 belongs to the lipoma HMGIC fusion partner-like (LHFPL) family, which is associated with transmembrane channel interactions. Structurally, it contains conserved transmembrane domains and cytoplasmic regions that facilitate protein-protein interactions. Research suggests its potential role in auditory function, particularly in cochlear hair cells, where it may stabilize or regulate mechanosensitive channels like TMC1. Recombinant FLJ22655 is typically produced using heterologous expression systems (e.g., HEK293 or E. coli) for functional studies. Despite limited understanding, its involvement in genetic hearing loss models highlights therapeutic relevance. Current studies focus on elucidating its precise molecular mechanisms, interactions, and disease associations. Advances in structural biology and gene-editing tools are expected to clarify its physiological and pathological roles.
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