| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FLJ22624 |
| Uniprot No | Q6PGQ7 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-551aa |
| 氨基酸序列 | MQITPETPGRIPVLNPFESPSDYSNLHEQTLASPSVFKSTKLPTPGKFRWSIDQLAVINPVEIDPEDIHRQALYLSHSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSQCHSSKCTNINSDSPVGKKLTIHSEKSDAACQTLLSLPVDFNLENILGDYFRADEFADQSPGNLSSSSLRRKLFLDGNGSISDSLPSASPGSPHSGVQTSLEMFYSIDLSPVKCRSPLQTPSSGQFSSSPIQASAKKYSLGSITSPSPISSPTFSPIEFQIGETPLSEQRKFTVHSPDASSGTNSNGITNPCIRSPYIDGCSPIKNWSPMRLQMYSGGTQYRTSVIQIPFTLETQGEDEEDKENIPSTDVSSPAMDAAGIHLRQFSNEASTHGTHLVVTAMSVTQNQSSASEKELALLQDVEREKDNNTVDMVDPIEIADETTWIKEPVDNGSLPMTDFVSGIAFSIENSHMCMSPLAESSVIPCESSNIQMDSGYNTQNCGSNIMDTVGAESYCKESDAQTCEVESKSQAFNMKQDHTTQRCWMKTASPFQCSSP |
| 分子量 | 86.35 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人FLJ22624蛋白的模拟参考文献示例(注：部分内容为假设性描述，实际文献需通过学术数据库核实)：
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1. **文献名称**：*Expression and Purification of Recombinant Human FLJ22624 Protein in E. coli*
**作者**：Zhang L., et al.
**摘要**：该研究报道了在大肠杆菌系统中高效表达重组人FLJ22624蛋白的方法，通过His标签纯化和质谱验证，为后续功能研究提供了可溶性蛋白样品。
2. **文献名称**：*Structural Insights into FLJ22624: A Bioinformatics Approach*
**作者**：Wang Y., et al.
**摘要**：利用生物信息学预测FLJ22624蛋白的三维结构及潜在功能域，提示其可能参与细胞代谢调控，并与线粒体膜蛋白存在相互作用。
3. **文献名称**：*FLJ22624 as a Potential Biomarker in Hepatocellular Carcinoma*
**作者**：Chen H., et al.
**摘要**：通过基因芯片和免疫组化分析，发现FLJ22624在肝癌组织中显著高表达，可能与肿瘤细胞增殖和转移相关，提示其作为治疗靶点的潜力。
4. **文献名称**：*FLJ22624 Interacts with ATP Synthase Subunits: A Proteomic Study*
**作者**：Kimura T., et al.
**摘要**：采用免疫共沉淀结合质谱技术，筛选出FLJ22624与ATP synthase复合体亚基的相互作用，推测其在能量代谢中发挥辅助作用。
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**说明**：上述文献为模拟内容，真实研究需通过**PubMed**或**Web of Science**以“FLJ22624”(或更新后的基因名称，如C1orf123)为关键词检索。若文献稀少，可扩展至相关蛋白家族或高通量研究中的数据提及。
Recombinant human FLJ22624 protein is a genetically engineered protein derived from the FLJ22624 gene, which encodes a hypothetical protein with limited functional characterization in current scientific literature. The FLJ22624 gene, also annotated as C16orf72 (Chromosome 16 Open Reading Frame 72), is conserved across vertebrates but remains poorly understood in terms of its physiological role. Its mRNA expression has been detected in various tissues, suggesting potential involvement in basic cellular processes, though specific mechanisms are yet to be elucidated.
The recombinant protein is typically produced using heterologous expression systems (e.g., E. coli, mammalian cells) to enable biochemical and functional studies. Bioinformatics analyses predict structural features such as potential transmembrane domains or phosphorylation sites, implying possible roles in signal transduction or protein-protein interactions. Limited experimental evidence associates FLJ22624 with cellular stress responses and metabolic regulation, but these findings require further validation.
Interest in recombinant FLJ22624 primarily stems from its inclusion in large-scale proteomic studies and disease biomarker screenings. Some transcriptomic datasets suggest altered expression patterns in cancers or neurological disorders, prompting investigations into its diagnostic or therapeutic potential. However, the lack of specific antibodies and functional assays has hindered progress. Current research focuses on characterizing its subcellular localization, interacting partners, and post-translational modifications to unravel its biological significance. As a recombinant product, it serves as a critical tool for antibody development and mechanistic studies aiming to decode this understudied protein's contribution to human physiology and pathology.
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