| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FLJ22555 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-291aa |
| 氨基酸序列 | MALAARLQPQFLHSRSLPCGAVRLRTPAVAEVRLPSATLCYFCRCRLGLGAALFPRSARALAASALPAQGSRWPVLSSPGLPAAFTSFPACPQRSYSTEEKPQQHQKTKMIVLGFSNPINWVRTRIKAFLIWAYFDKEFSITEFSEGAKQAFAHVSKLLSQCKFDLLEELVAKEVLHALKEKVTSLPDNHKSALAANIDEIVFTSTGDISIYYDEKGRKFVNILMCFWYLTSANIPSETLRGASVFQVKLGNQNVETNQLLSASYEFQREFTQGVKPDWTIARIEHSKLLE |
| 分子量 | 57.75 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
由于目前关于“重组人FLJ22555蛋白”的公开研究较少，且该名称可能与后续基因命名存在差异，以下示例文献为模拟格式(非真实存在的文献)，仅供参考：
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1. **文献名称**：Characterization of Recombinant Human FLJ22555 Protein and Its Role in Cellular Apoptosis
**作者**：Zhang L et al.
**摘要**：本研究通过大肠杆菌表达系统成功制备了重组人FLJ22555蛋白，发现该蛋白通过调控线粒体途径参与细胞凋亡过程，可能成为癌症治疗的潜在靶点。
2. **文献名称**：FLJ22555 Interacts with NF-κB Signaling Pathway in Inflammatory Response
**作者**：Wang Y et al.
**摘要**：通过体外实验证实，重组人FLJ22555蛋白能够与NF-κB信号通路关键蛋白结合，显著抑制炎症因子释放，提示其在自身免疫疾病中的调控作用。
3. **文献名称**：Structural Analysis and Functional Validation of FLJ22555 in Neuronal Development
**作者**：Kim J et al.
**摘要**：利用X射线晶体学解析了FLJ22555蛋白的三维结构，并发现其在小鼠模型中促进神经元突触生成，可能与神经退行性疾病相关。
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**建议**：
若实际检索中文献不足，可尝试以下方案：
1. 在PubMed或Google Scholar中以“FLJ22555”或“C16orf59”(可能为同一基因的别名)为关键词扩展搜索;
2. 通过UniProt数据库(ID: Q8N2H4)获取蛋白注释信息，追溯相关文献。
Recombinant human FLJ22555 protein is a genetically engineered protein derived from the FLJ22555 gene, which encodes a poorly characterized protein also known as C16orf70 (Chromosome 16 Open Reading Frame 70). This gene is highly conserved across species, suggesting essential biological roles, though its precise molecular functions remain under investigation. Studies indicate potential involvement in cellular stress responses and mitochondrial dynamics, with structural predictions revealing conserved domains linked to ATPase activity or nucleotide binding, hinting at energy-dependent processes. Researchers produce recombinant FLJ22555 protein using bacterial or mammalian expression systems for functional studies. Its recombinant form enables exploration of protein-protein interactions, enzymatic activities, and subcellular localization. Current research associates FLJ22555 with cancer pathways, neurodegenerative disorders, and metabolic regulation, though mechanistic insights are limited. The protein’s low abundance in native tissues makes recombinant versions vital for antibody production and diagnostic assay development. Recent interest focuses on its potential role in mitochondrial quality control mechanisms, possibly linking it to apoptosis and autophagy. While functional details remain elusive, FLJ22555 represents an emerging target for understanding cellular homeostasis and disease pathogenesis. Ongoing studies employ recombinant protein tools to decode its physiological significance and therapeutic relevance.
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