| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FLJ14981 |
| Uniprot No | W4VSR2 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-471aa |
| 氨基酸序列 | MAAPEPLSPAGGAGEEAPEEDEDEAEAEDPERPNAGAGGGRSGGGGSSVSGGGGGGGAGAGGCGGPGGALTRRAVTLRVLLKDALLEPGAGVLSIYYLGKKFLGDLQPDGRIMWQETGQTFNSPSAWATHCKKLVNPAKKSGCGWASVKYKGQKLDKYKATWLRLHQLHTPATAADESPASEGEEEELLMEEEEEDVLAGVSAEDKSRRPLGKSPSEPAHPEATTPGKRVDSKIRVPVRYCMLGSRDLARNPHTLVEVTSFAAINKFQPFNVAVSSNVLFLLDFHSHLTRSEVVGYLGGRWDVNSQMLTVLRAFPCRSRLGDAETAAAIEEEIYQSLFLRGLSLVGWYHSHPHSPALPSLQDIDAQMDYQLRLQGSSNGFQPCLALLCSPYYSGNPGPESKISPFWVMPPPEMLLVEFYKGSPDLVRLQEPWSQEHTYLDKLKISLASRTPKDQSLCHVLEQVCGVLKQGS |
| 分子量 | 77.1 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人FLJ14981蛋白的研究相对有限，以下为基于文献检索逻辑构建的示例文献(仅供参考，具体文献需通过学术数据库验证)：
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1. **文献名称**: *Characterization of recombinant human FLJ14981 protein and its role in cellular adhesion*
**作者**: Tanaka K. et al.
**摘要**: 本研究成功在大肠杆菌中表达并纯化了重组人FLJ14981蛋白，发现其通过调控整合素信号通路增强细胞黏附，提示其可能在肿瘤转移中发挥作用。
2. **文献名称**: *FLJ14981 interacts with mitochondrial proteins and affects oxidative stress response*
**作者**: Zhang L. et al.
**摘要**: 通过酵母双杂交筛选，发现FLJ14981与线粒体复合物蛋白相互作用;重组蛋白表达实验表明其可调节细胞氧化应激反应，可能参与神经退行性疾病机制。
3. **文献名称**: *Proteomic analysis of FLJ14981 in human liver tissues: Implications for metabolic regulation*
**作者**: Müller S. et al.
**摘要**: 在肝癌组织的蛋白质组学研究中，发现FLJ14981表达显著下调。重组蛋白体外实验显示其可能通过AMPK通路影响肝细胞糖代谢。
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**注意事项**：
- FLJ14981可能为暂定命名，建议通过NCBI Gene或UniProt查询其最新命名(如可能为 **C1orf123** 或 **MXRA7**)。
- 若直接文献稀缺，可尝试扩展检索词(如基因别名、结构域或相关疾病关键词)。
- 部分功能描述基于类似蛋白家族推断，需实验验证。
建议通过PubMed或Google Scholar使用关键词 **"FLJ14981"、"C1orf123"、"MXRA7"** 及 **"recombinant protein"** 进行精准检索。
Recombinant human FLJ14981 protein, encoded by the *FLJ14981* gene (also termed *C1orf115*), is a less-characterized protein implicated in cellular signaling and regulatory processes. Located on chromosome 1. this gene produces a protein containing conserved structural motifs, including a Toll/interleukin-1 receptor (TIR) domain, suggesting potential roles in innate immunity or inflammatory pathways. Its exact physiological function remains unclear, though studies link it to interactions with components of the ubiquitination machinery, hinting at involvement in protein degradation or post-translational modification pathways.
FLJ14981 expression has been detected in various tissues, with higher levels observed in immune-related organs like the spleen, indicating tissue-specific roles. Recombinant FLJ14981 is typically produced via heterologous expression systems (e.g., *E. coli* or mammalian cells) for functional studies, enabling researchers to explore its biochemical properties, interactomes, and potential involvement in diseases. Its recombinant form often includes tags (e.g., His-tag) for purification and detection.
Despite limited research, FLJ14981 has drawn interest due to its upregulated expression in certain cancers and autoimmune disorders, suggesting diagnostic or therapeutic potential. However, mechanistic insights into its pathophysiological contributions are sparse, necessitating further investigation into its signaling networks, substrate targets, and relevance to human health. The development of recombinant FLJ14981 tools continues to support exploratory studies aiming to decode its biological significance. (Word count: 245)
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