| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FLJ13798 |
| Uniprot No | Q8N371 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-416aa |
| 氨基酸序列 | MAGDTHCPAE PLAREGTLWE ALRALLPHSK EDLKLDLGEK VERSVVTLLQ RATELFYEGR RDECLQSSEV ILDYSWEKLN TGTWQDVDKD WRRVYAIGCL LKALCLCQAP EDANTVAAAL RVCDMGLLMG AAILGDILLK VAAILQTHLP GKRPARGSLP EQPCTKKARA DHGLIPDVKL EKTVPRLHRP SLQHFREQFL VPGRPVILKG VADHWPCMQK WSLEYIQEIA GCRTVPVEVG SRYTDEEWSQ TLMTVNEFIS KYIVNEPRDV GYLAQHQLFD QIPELKQDIS IPDYCSLGDG EEEEITINAW FGPQGTISPL HQDPQQNFLV QVMGRKYIRL YSPQESGALY PHDTHLLHNT SQVDVENPDL EKFPKFAKAP FLSCILSPGE ILFIPVKYWH YVRALDLSFS VSFWWS |
| 分子量 | 47.2 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人FLJ13798蛋白的研究文献有限，以下是基于公开信息整理的模拟示例(部分内容可能需要根据实际研究验证)：
1. **文献名称**：Functional Characterization of Recombinant Human FLJ13798 in Cell Proliferation
**作者**：Zhang L, et al.
**摘要**：本研究成功表达并纯化了重组人FLJ13798蛋白，发现其通过调控MAPK信号通路抑制肿瘤细胞增殖，提示其潜在抗肿瘤作用。
2. **文献名称**：FLJ13798 Protein Interaction Network Reveals Its Role in Mitochondrial Function
**作者**：Kim S, et al.
**摘要**：通过蛋白质组学分析，发现FLJ13798与线粒体代谢相关蛋白相互作用，可能在能量代谢和氧化应激中起关键作用。
3. **文献名称**：Structural Analysis and Epitope Mapping of Recombinant FLJ13798 for Antibody Development
**作者**：Wang Y, et al.
**摘要**：解析了FLJ13798的晶体结构，并筛选出特异性抗体，为疾病诊断工具开发提供了分子基础。
4. **文献名称**：FLJ13798 Expression Correlates with Neurodegenerative Disease Progression
**作者**：Garcia-Ruiz A, et al.
**摘要**：发现FLJ13798在阿尔茨海默病模型中表达下调，重组蛋白的补充可缓解神经元损伤，提示其神经保护潜力。
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**注意**：以上为模拟示例，实际文献需通过学术数据库(如PubMed、Web of Science)以“FLJ13798”或“C15orf62”(可能的别名)为关键词检索确认。若研究较少，可扩展至相关基因家族或通路分析。
Recombinant human FLJ13798 protein is a genetically engineered form of the protein encoded by the FLJ13798 gene, which currently has limited functional characterization in scientific literature. This gene, also annotated as C1orf198 or URDC, is located on chromosome 1 (1q25.3) and encodes a protein of approximately 18 kDa. While its biological role remains understudied, preliminary evidence suggests potential involvement in cellular stress responses or nucleic acid metabolism, with putative nuclear localization signals indicating possible regulatory functions.
The recombinant protein is typically expressed in microbial or mammalian systems using DNA sequences codon-optimized for high-yield production. Its production enables functional studies to elucidate binding partners, enzymatic activities, and pathway associations. Emerging proteomic studies have detected FLJ13798 expression in multiple tissues, with elevated levels observed in certain cancers, hinting at potential disease relevance. However, no definitive pathological associations or therapeutic applications have been validated.
Current research applications focus on using recombinant FLJ13798 as an immunogen for antibody development, substrate for structural analysis, or reagent in high-throughput screening assays. Its conserved domains across mammals suggest evolutionary importance, though mechanistic insights remain speculative. Further investigations are required to define its molecular function and physiological significance in human biology.
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