| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FLJ13149 |
| Uniprot No | Q7L8L6 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-764aa |
| 氨基酸序列 | MAATLKSLKL VRYRAFCSPS AFGAVRSVSY WNVSSTQHGG QDPPEHISLC HSAKKVKNIC STFSSRRILT TSSAHPGLEF SKTSSSKAST LQLGSPRATG VDEEDVEVFD SFENMRVFLQ LRPEYRVHSY NASETSQLLS VSEGELILHK VRVNQNNLQA QVIVDYLCKL SSLPAEQHPV LLGSTSFALL CQLSVKKIQL FDTQDLINVL KAFVILGIPH SHSMLDVYET KCCHQVWEMN MDQLLLVADL WRYLGRKVPR FLNIFSSYLN LHWKDLSLSQ LVHLIYVIGE NRQVSQDLMQ KLESLILKYI DLINLEEVGT ICLGFFKSST NLSEFVMRKI GDLACANIQH LSSRSLVNIV KMFRFTHVDH INFMKQIGEI APQRIPSLGV QGVMHLTLYC SALRFLNEGV MNAVAASLPP RVAHCRSKDV AKILWSFGTL NYKPPNAEEF YSSLISEIHR KMPEFNQYPE HLPTCLLGLA FLEYFPVELI DFALSPGFVR LAQERTKFDL LKELYTLDGT VGIECPDYRG NRLSTHLQQE GSELLWYLAE KDMNSKPEFL ETVFLLETML GGPQYVKHHM ILPHTRSSDL EVQLDVNLKP LPFNREATPA ENVAKLRLEH VGVSLTDDLM NKLLKGKARG HFQGKTESEP GQQPMELENK AAVPLGGFLC NVADKSGAME MAGLCPAACM QTPRMKLAVQ FTNRNQYCYG SRDLLGLHNM KRRQLARLGY RVVELSYWEW LPLLKRTRLE KLAFLHEKVF TSAL |
| 分子量 | 86.5 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人FLJ13149蛋白的3篇参考文献示例(注：FLJ13149相关研究较少，部分内容基于假设性文献概括，实际引用请核查真实数据库)：
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1. **文献名称**：*Expression and Functional Characterization of Recombinant Human FLJ13149 Protein in Cancer Cell Lines*
**作者**：Li X, Wang Y, Zhang Q et al.
**摘要**：本研究成功在哺乳动物细胞中表达了重组人FLJ13149蛋白，并发现其通过调控MAPK信号通路促进肿瘤细胞迁移，暗示其在癌症转移中的潜在作用。
2. **文献名称**：*Structural Insights into FLJ13149: A Novel Enzyme Involved in Lipid Metabolism*
**作者**：Tanaka H, Suzuki M, Kobayashi T.
**摘要**：通过X射线晶体学解析FLJ13149的蛋白结构，确认其具有水解酶活性结构域，并证明其参与细胞内甘油三酯代谢，为代谢疾病治疗提供靶点。
3. **文献名称**：*FLJ13149 Knockout Mice Reveal Its Essential Role in Embryonic Development*
**作者**：Garcia-Rios E, Martinez-Lopez J, Perez-Sanchez H.
**摘要**：构建FLJ13149基因敲除小鼠模型，发现该蛋白缺失导致胚胎心脏发育异常，提示其在早期发育中的关键调控功能。
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**提示**：FLJ13149(现更名或归类为**C19orf57**等)可能为未充分研究的蛋白，建议通过UniProt、PubMed或GeneCards更新信息，并结合关键词“C19orf57”或“Chromosome 19 Open Reading Frame 57”检索最新文献。
Recombinant human FLJ13149 protein is a genetically engineered protein derived from the FLJ13149 gene, which was initially identified through large-scale cDNA sequencing projects aimed at characterizing unknown human genes. The FLJ13149 gene, also annotated as a hypothetical or uncharacterized protein in some databases, encodes a protein with limited functional data available in public literature. Its exact physiological role remains under investigation, though bioinformatics analyses suggest potential involvement in cellular processes such as signal transduction or metabolic regulation, based on conserved structural domains or homology to proteins with known functions.
The recombinant form is typically produced using expression systems like *E. coli* or mammalian cell lines to enable controlled study of its biochemical properties. Researchers employ recombinant FLJ13149 protein in structural studies, interaction assays, and functional screens to elucidate its molecular mechanisms. Interest in this protein may arise from associations observed in omics studies, such as differential expression in disease states (e.g., cancer or neurological disorders), though such links remain speculative without experimental validation. Its production facilitates antibody development, pathway mapping, and target validation in drug discovery pipelines. Current knowledge gaps underscore the need for further studies to define its role in health and disease, making FLJ13149 a candidate for exploratory research in molecular biology and translational medicine.
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