关键信息
-
基因名
ANP32E
- 应用
-
别名
Acidic leucine-rich nuclear phosphoProtein 32 family member E; AN32E_HUMAN; anp32e
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9BTT0
-
表达区间
1-268aa
-
氨基酸序列
MEMKKKINLE LRNRSPEEVT ELVLDNCLCV NGEIEGLNDT FKELEFLSMA NVELSSLARL PSLNKLRKLE LSDNIISGGL EVLAEKCPNL TYLNLSGNKI KDLSTVEALQ NLKNLKSLDL FNCEITNLED YRESIFELLQ QITYLDGFDQ EDNEAPDSEE EDDEDGDEDD EEEEENEAGP PEGYEEEEEE EEEEDEDEDE DEDEAGSELG EGEEEVGLSY LMKEEIQDEE DDDDYVEEGE EEEEEEEGGL RGEKRKRDAE DDGEEEDD
-
分子量
30 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ANP32E, a member of the ANP32 family of acidic nuclear proteins, has garnered attention in recent years due to its pivotal role in various cellular processes, including transcription regulation, apoptosis, and cellular proliferation. These proteins are characterized by their acidic nature and their ability to interact with a variety of cellular partners, including chromatin-associated proteins and components of the transcriptional machinery. The research surrounding ANP32E has revealed its involvement in the modulation of several key signaling pathways, particularly those related to cell survival and stress responses. Notably, dysregulation of ANP32E expression has been linked to various pathological conditions, such as cancer, where it may influence tumorigenesis and resistance to chemotherapy. Studies have also suggested that ANP32E may play a role in the immune response, potentially affecting inflammation and immune cell function. The recombinant expression of ANP32E allows for detailed functional analyses, facilitating the exploration of its biochemical properties and interactions in cellular contexts. Investigating ANP32E not only enhances our understanding of its fundamental biological roles but also opens avenues for therapeutic strategies that target its pathways in disease conditions. Consequently, ongoing research aims to elucidate the precise mechanisms through which ANP32E exerts its effects and to identify potential clinical implications for manipulating its activity in various diseases.
