| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | CTAGE5 |
| Uniprot No | Q96PC5 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-809aa |
| 氨基酸序列 | MEEPGATPQPDLGLLLEELRRVVAALPEGMRPDSNLYGFPWELVICAAVVGFFAVLFFLWRSFRSVRSRLYVGREKKLALMLSGLIEEKSKLLEKFSLVQKEYEGYEVESSLKDASFEKEATEAQSLEVENQMATCEKLNRSNSELEDEILCLEKELKEEKSKHSEQDELMADISKRIQSLEDESKSLKSQVAEAKMTFKIFQMNEERLNIAIKDALNENSQLQESQKQLLQEAEVWKEQVSELNKQKVTFEDSKVHAEQVLNDKESHIKTLTERLLKMKDWAAMLGEDITDDDNLELEMNSESENGAYLDNPPKGALKKLIHAAKLNASLKTLEGERNQIYIQLSEVDKTKEELTEHIKNLQTEQASLQSENTHFENENQKLQQKLKVMTELYQENEMKLHRKLTVEENYRLEKEEKLSKVDEKISHATEELETYRKRAKDLEEELERTIHSYQGQIISHEKKAHDNWLAARNAERNLNDLRKENAHNRQKLTETELKFELLEKDPYALDVPNTAFGREHSPYGPSPLGWPSSETRAFLSPPTLLEGPLRLSPLLPGGGGRGSRGPGNPLDHQITNERGESSCDRLTDPHRAPSDTGSLSPPWDQDRRMMFPPPGQSYPDSALPPQRQDRFCSNSGRLSGPAELRSFNMPSLDKMDGSMPSEMESSRNDTKDDLGNLNVPDSSLPAENEATGPGFVPPPLAPVRGPLFPVDARGPFLRRGPPFPPPPPGAMFGASRDYFPPGDFPGPPPAPFAMRNVYPPRGFPPYLPPRPGFFPPPPHSEGRSEFPSGLIPPSNEPATEHPEPQQET |
| 分子量 | 89 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人CTAGE5蛋白的公开研究文献较为有限，以下为模拟示例(仅供参考，非真实文献)：
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1. **文献名称**：*Expression and Functional Characterization of Recombinant Human CTAGE5 in Cancer Cell Lines*
**作者**：Zhang L., et al.
**摘要**：研究利用HEK293细胞成功表达重组人CTAGE5蛋白，并通过免疫共沉淀证实其与自噬相关蛋白LC3的相互作用，提示其在肿瘤细胞自噬调控中的潜在作用。
2. **文献名称**：*Structural Analysis of CTAGE5 Reveals a Role in Vesicular Trafficking*
**作者**：Kimura T., et al.
**摘要**：通过大肠杆菌系统表达并纯化重组CTAGE5蛋白，结合X射线晶体学解析其结构，发现其N端结构域可能参与细胞内囊泡运输的分子机制。
3. **文献名称**：*CTAGE5 as a Biomarker in Melanoma: Recombinant Protein-Based Serological Screening*
**作者**：Garcia R., et al.
**摘要**：通过昆虫细胞表达重组CTAGE5.开发ELISA检测方法，发现其在黑色素瘤患者血清中显著高表达，或可作为诊断标志物。
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**说明**：目前CTAGE5的研究较少，建议通过以下途径获取最新进展：
- 使用PubMed、Google Scholar等平台搜索关键词**"CTAGE5 recombinant"**或**"CTAGE5 function"**。
- 关注癌症睾丸抗原(Cancer-Testis Antigen)或胞内运输相关领域的研究。
- 查阅预印本平台(如bioRxiv)或联系相关作者获取未发表数据。
**Background of Recombinant Human CTAGE5 Protein**
The CTAGE5 (Cutaneous T-cell lymphoma-associated antigen 5) protein belongs to the CTAGE family, a group of transmembrane proteins implicated in cellular processes such as vesicular trafficking, protein-protein interactions, and possibly cancer progression. CTAGE5 is encoded by the *CTAGE5* gene, located on chromosome 7 in humans, and shares structural features with other CTAGE members, including coiled-coil domains and transmembrane regions. While its precise physiological role remains unclear, CTAGE5 has been linked to neurodevelopmental processes and cancer, with elevated expression observed in malignancies like melanoma and hepatocellular carcinoma.
Recombinant human CTAGE5 protein is engineered in vitro using expression systems (e.g., *E. coli* or mammalian cells) to produce purified, biologically active forms for functional studies. It serves as a critical tool for investigating CTAGE5's molecular interactions, signaling pathways, and potential roles in disease mechanisms. Studies focus on its involvement in intracellular transport, immune evasion in cancers, and interactions with cytoskeletal components. Additionally, recombinant CTAGE5 aids in antibody development for diagnostic or therapeutic applications. Further research is needed to fully elucidate its functional significance and therapeutic potential.
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