关键信息
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基因名
STX1A
- 应用
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别名
STX1A；STX1；Syntaxin-1A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q16623
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表达区间
1-265aa
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氨基酸序列
MKDRTQELRTAKDSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAEN VEEVKRKHSAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSI EQEEGLNRSSADLRIRKTQHSTLSRKFVEVMSEYNATQSDYRERCKGRIQ RQLEITGRTTTSEELEDMLESGNPAIFASGIIMDSSISKQALSEIETRHS EIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVEHAVDYVERAVSD TKKAVKYQSKARRKK
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分子量
31 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
STX1A (Syntaxin 1A) is a member of the syntaxin family of proteins, which play a crucial role in the process of synaptic vesicle exocytosis, a fundamental mechanism for neurotransmitter release in neuronal communication. The proper functioning of STX1A is essential for the regulation of synaptic transmission, influencing various physiological processes, including learning and memory. Dysregulation or mutations in STX1A have been implicated in several neurological disorders and synaptic dysfunctions, making it a significant target for research. Studies have shown that STX1A interacts with other proteins in the SNARE complex, facilitating the fusion of synaptic vesicles with the presynaptic membrane. The recombinant expression of STX1A protein allows for detailed investigation of its functional properties, structural analysis, and interaction with other molecular partners. Understanding the role of STX1A through recombinant protein studies could provide insights into the molecular mechanisms underlying neuronal signaling and may aid in the development of therapeutic strategies for related neuropsychiatric and neurodegenerative conditions. Overall, research on STX1A recombinant proteins holds promise for enhancing our comprehension of synaptic biology and the intricate pathways of neurotransmission.
