关键信息
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基因名
AHDC1
- 应用
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别名
AHDC1; AHDC1_HUMAN; AT-hook DNA-binding motif-containing Protein 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q5TGY3
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表达区间
1-399aa
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氨基酸序列
MMDWNEASSAPGYNWNQSVLFQSSSKPGRGRRKKVDLFEASHLGFPTSASAAASGYPSKRSTGPRQPRGGRGGGACSAKKERGGAAAKAKFIPKPQPVNPLFQDSPDLGLDYYSGDSSMSPLPSQSRAFGVGERDPCDFIGPYSMNPSTPSDGTFGQGFHCDSPSLGAPELDGKHFPPLAHPPTVFDAGLQKAYSPTCSPTLGFKEELRPPPTKLAACEPLKHGLQGASLGHAAAAQAHLSCRDLPLGQPHYDSPSCKGTAYWYPPGSAARSPPYEGKVGTGLLADFLGRTEAACLSAPHLASPPATPKADKEPLEMARPPGPPRGPAAAAAGYGCPLLSDLTLSPVPRDSLLPLQDTAYRYPGFMPQAHPGLGGGPKSGFLGPMAEPHPEDTFTVTSL
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分子量
68.1 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
AHDC1 (AT-Hook DNA-Binding Motif Containing Protein 1) is an important protein implicated in various cellular processes, including DNA repair, chromatin remodeling, and regulation of gene expression. The study of AHDC1 is particularly significant due to its association with several pathological conditions, including developmental disorders and cancer. Mutations in the AHDC1 gene have been linked to syndromic intellectual disability, highlighting its crucial role in normal brain development and function. Research has focused on understanding the structural and functional characteristics of AHDC1, particularly its interaction with DNA and other cellular partners. Recombinant AHDC1 protein is thus essential for investigating its molecular mechanisms and potential therapeutic applications. Such studies aim to elucidate how AHDC1 operates at the cellular level, which may lead to new insights into treatment strategies for diseases related to AHDC1 dysfunction. Overall, the generation and characterization of AHDC1 recombinant protein mark a pivotal step in advancing our understanding of this multifunctional protein and its implications in human health and disease.
