关键信息
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基因名
STAC
- 应用
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别名
STAC;STAC1;SH3 and cysteine-rich domain-containing Protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q99469
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表达区间
1-402aa
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氨基酸序列
MGSSHHHHHHSSGLVPRGSHMGSMIPPSSPREDGVDGLPKEAVGAEQPPS PASTSSQESKLQKLKRSLSFKTKSLRSKSADNFFQRTNSEDMKLQAHMVA EISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIFKKPTFCDVCNHM IVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPLLI HEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHR TSTSDLVEVPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQ GSLSKDPLQMNTYVALYKFVPQENEDLEMRPGDIITLLEDSNEDWWKGKI QDRIGFFPANFVQRLQQNEKIFRCVRTFIGCKEQGQITLKENQICVSSEE EQDGFIRVLSGKKKGLIPLDVLENI
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分子量
47 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
STAC (Signal Transduction and Activation of RNA) proteins are a family of signaling molecules that play a significant role in cancer biology and other cellular processes. They are known for their ability to interact with various signaling pathways, influencing gene expression and cellular responses. Recent studies have suggested that STAC proteins may serve as important regulators of cell growth, differentiation, and survival, particularly in the context of tumor development and progression. Research has shown that alterations in STAC protein expression can lead to dysregulation of these pathways, contributing to the transformation of normal cells into cancerous ones. Moreover, the potential of STAC proteins as therapeutic targets has garnered attention, as manipulating their function could provide new avenues for cancer treatment. Scientists are actively investigating the molecular mechanisms by which STAC proteins exert their effects, as well as their interactions with other cellular components. Understanding STAC protein dynamics and their role in disease could lead to the development of novel diagnostic and therapeutic strategies, ultimately improving patient outcomes in various malignancies.
